Oxytocin imprinted polymer based surface plasmon resonance sensor and its application to milk sample

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dc.contributor.authorYola, Mehmet Lutfi
dc.contributor.authorAtar, Necip
dc.contributor.authorErdem, Arzum
dc.date.accessioned2019-10-27T22:58:51Z
dc.date.available2019-10-27T22:58:51Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstractIn present study, a novel and sensitive molecular imprinted surface plasmon resonance sensor was prepared by fabricating a self-assembling monolayer formation of allylmercaptane on gold chip surface for selective determination of oxytocin in milk. Then, oxytocin-imprinted poly (2-hydroxyethyl methacrylate-methacryloylamidoglutamic acid) nanofilm was performed onto the allyl mercaptane modified chip. The unmodified and modified surfaces were characterized by using Fourier transform infrared spectroscopy, atomic force microscopy, ellipsometry, scanning electron microscope and contact angle measurements. The imprinted surface plasmon resonance sensor was found to be sensitive, selective, linear and proper. The linearity range in the concentration range of oxytocin was obtained as 0.01-1.0 ng/mL and the detection limit of the prepared sensor was calculated as 0.0030 ng/mL. The molecular imprinted sensor based on surface plasmon resonance was also applied successfully to milk sample for the determination of oxytocin. Furthermore, the repeatability of the prepared molecular imprinted sensor was studied. The good repeatability of the prepared oxytocin-imprinted surface plasmon resonance sensors makes them attractive in sensor studies. In addition, isotherm models were applied to data to explain adsorption process. (C) 2015 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipDumlupinar UniversityDumlupinar University; Pamukkale UniversityPamukkale University; [2014HZL023]en_US
dc.description.sponsorshipAuthors thank Dumlupinar University and Pamukkale University for the equipments and also the financial support through by project grant (Project No: 2014HZL023).en_US
dc.identifier.doi10.1016/j.snb.2015.07.004
dc.identifier.endpage848en_US
dc.identifier.issn0925-4005
dc.identifier.issn0925-4005en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage842en_US
dc.identifier.urihttps://doi.org/10.1016/j.snb.2015.07.004
dc.identifier.urihttps://hdl.handle.net/11454/51659
dc.identifier.volume221en_US
dc.identifier.wosWOS:000362918100109en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Saen_US
dc.relation.ispartofSensors and Actuators B-Chemicalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOxytocinen_US
dc.subjectSurface plasmon resonanceen_US
dc.subjectMolecular imprintingen_US
dc.subjectValidationen_US
dc.titleOxytocin imprinted polymer based surface plasmon resonance sensor and its application to milk sampleen_US
dc.typeArticleen_US

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