In vitro Antimicrobial Susceptibility of Urinary Tract Infection Pathogens in Children

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dc.authoridAydemir, Sabire Sohret/0000-0001-8354-9100
dc.authoridOzgur, Su/0000-0002-8993-674X
dc.contributor.authorTaner, Sevgin
dc.contributor.authorAydemir, Sabire Sohret
dc.contributor.authorOzgur, Su
dc.contributor.authorAksoy, Ezgi
dc.contributor.authorKeskinoglu, Ahmet
dc.contributor.authorTunger, Alper
dc.contributor.authorKabasakal, Caner
dc.date.accessioned2024-08-31T07:47:01Z
dc.date.available2024-08-31T07:47:01Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: Urinary tract infection (UTI) is one of the most common bacterial infections in children. Empirical treatment is commenced according to the patient's characteristics and the antimicrobial susceptibility patterns in the region. Therefore, a determination of antimicrobial resistance patterns has a great importance in effective treatment. The aim of this study was to determine the pathogens which cause UTIs in patients admitted to a university hospital in Izmir and to determine their antimicrobial susceptibility pattern. Materials and Metkods: The files of patients aged between 0-18 years, followed up with a diagnosis of UTI, vesicoureteral reflux and neurogenic bladder in Ege University Faculty of Medicine Paediatric Nephrology Unit between February, 2013 and November, 2018 were retrospectively reviewed.Results: A total of 1,126 positive urine cultures from 729 patients (65% female) were included in this study. Gram-negative pathogens constituted 88.2% of the cultures. Escherichia coli (E. coli) was the most commonly isolated bacteria with a prevalence of 59.1%, followed by Klebsiella pneumonia with 17.9%, and Enterococcus faecalis with 8.3% (n=93). Ampicillin, cefuroxime and trimethoprim-sulfamethoxazole with susceptibility rates of 18.6%, 39.6%, 49.0% respectively, constituted the highest resistant antimicrobials to Enterobacteriaceae. Enterococcus spp. showed the highest resistance to gentamycin with 50% resistance in tested cases. Pseudomonas spp. with 64.3% susceptibility showed the highest resistance to piperacillin-tazobactam.Conclusion: This study revealed that bacterial resistance to commonly used antimicrobials in UTI is an important and challenging problem which requires planning.en_US
dc.identifier.doi10.4274/jpr.galenos.2023.25986
dc.identifier.endpage215en_US
dc.identifier.issn2147-9445
dc.identifier.issue3en_US
dc.identifier.startpage210en_US
dc.identifier.urihttps://doi.org/10.4274/jpr.galenos.2023.25986
dc.identifier.urihttps://hdl.handle.net/11454/104288
dc.identifier.volume10en_US
dc.identifier.wosWOS:001144653500005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofJournal of Pediatric Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240831_Uen_US
dc.subjectAntibiotic Resistanceen_US
dc.subjectAntimicrobial Resistanceen_US
dc.subjectAntimicrobial Susceptibilityen_US
dc.subjectE. Colien_US
dc.subjectPaediatricen_US
dc.subjectUrinary Tract Infectionsen_US
dc.subjectUrine Cultureen_US
dc.titleIn vitro Antimicrobial Susceptibility of Urinary Tract Infection Pathogens in Childrenen_US
dc.typeArticleen_US

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