Design of a new generation wound dressing with pine bark extract

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dc.authorscopusid54684986800
dc.authorscopusid57196860546
dc.authorscopusid6602338711
dc.authorscopusid22837401200
dc.contributor.authorKarakaya P.S.
dc.contributor.authorOktay A.
dc.contributor.authorSeventekin N.
dc.contributor.authorYesil-Celiktas O.
dc.date.accessioned2023-01-12T20:23:37Z
dc.date.available2023-01-12T20:23:37Z
dc.date.issued2021
dc.departmentN/A/Departmenten_US
dc.description.abstractMedical textiles are one of the fastest growing sectors in the technical textile market. Wound dress is one of the significant applications with the largest share in medical textiles. Active molecules doped in the dressings may be therapeutic agents, vitamins, antibiotics, minerals, and growth factors, which contribute to wound healing. Medical plants have a great potential with positive effects in wound care and accelerate the rate of wound healing. Pine bark, which is known to exhibit wound healing properties, is also used in the medical field. The purpose of this study is to design a new wound dressing enriched with Pinus brutia extract. Microwave-assisted extraction which is an environmentally friendly method was carried out at 70?, 900 W for 10 min to obtain the extracts. Subsequently, P. brutia bark extract was embedded to the alginate gel dressing and characterized and evaluated by in vivo studies on rats. According to the results, the extract was rapidly released from the alginate gel in the first 6 h, whereas the release was slowly increased to 24 h and then reached a steady state. Therefore, P. brutia extract-embedded alginate gel dressings applied for in vivo studies were changed every 24 h, reaching a healing rate of 75.7%, whereas the control group showed a healing rate of 48.6% indicating the superiority of the newly designed wound healing dress enriched with pine bark extract. © The Author(s) 2019.en_US
dc.description.sponsorshipEge Üniversitesi: 15MUH051en_US
dc.description.sponsorshipThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The authors would like to acknowledge the financial support from Research Fund of Ege University through 15MUH051 project.en_US
dc.identifier.doi10.1177/1528083719855324
dc.identifier.endpage1204en_US
dc.identifier.issn15280837
dc.identifier.issn1528-0837en_US
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-85068674576en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1193en_US
dc.identifier.urihttps://doi.org/10.1177/1528083719855324
dc.identifier.urihttps://hdl.handle.net/11454/79735
dc.identifier.volume50en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSAGE Publications Ltden_US
dc.relation.ispartofJournal of Industrial Textilesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectalginate gelen_US
dc.subjectextractionen_US
dc.subjectpine barken_US
dc.subjectWound dressingen_US
dc.subjectAlginateen_US
dc.subjectExtractionen_US
dc.subjectTextilesen_US
dc.subjectActive moleculesen_US
dc.subjectAlginate gelen_US
dc.subjectMedical textilesen_US
dc.subjectMicrowave-assisted extractionen_US
dc.subjectPine barken_US
dc.subjectTechnical textilesen_US
dc.subjectTherapeutic agentsen_US
dc.subjectWound dressingsen_US
dc.subjectTissue regenerationen_US
dc.subjectAntibioticsen_US
dc.subjectBarken_US
dc.subjectExtractionen_US
dc.subjectGelsen_US
dc.subjectPinusen_US
dc.subjectPlantsen_US
dc.subjectSurgical Dressingsen_US
dc.subjectTextilesen_US
dc.titleDesign of a new generation wound dressing with pine bark extracten_US
dc.typeArticleen_US

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