Effect of Shorter Antimicrobial Prophylaxis and Pre-Intervention Measures on Infections Developing After Transrectal Prostate Biopsies

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dc.contributor.authorArda, Bilgin
dc.contributor.authorErdem, Huseyin Aytac
dc.contributor.authorKismali, Erkan
dc.contributor.authorAydemir, Sohret
dc.contributor.authorSimsir, Adnan
dc.contributor.authorTamsel, Sadik
dc.contributor.authorOzyurt, Ceyhun
dc.contributor.authorSipahi, Hilal
dc.contributor.authorSipahi, Oguz Resat
dc.contributor.authorUlusoy, Sercan
dc.date.accessioned2019-10-27T11:19:05Z
dc.date.available2019-10-27T11:19:05Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractIntroduction: Transrectal prostate biopsy (TPB) is currently a commonly used invasive procedure for the diagnosis of prostatic diseases. Due to increasing infectious complications after TPBs in our institute, it was decided to change antimicrobial prophylaxis regimens and pre-intervention measures. The aim of this study was to evaluate the effects of shorter antimicrobial prophylaxis, intestinal cleansing and single use sterile gels on infections developing after TPBs in our tertiary-care educational hospital. Materials and Methods: Infections developing in the last six months after TPB were evaluated retrospectively by using records of microbiology, radiology and urology departments. Sterilization and disinfection, antimicrobial prophylaxis regimens, intestinal decontamination procedures and routine biopsy procedures were reevaluated in cooperation with the corresponding clinics. Afterwards, it was decided to implement three changes in the TPB practice: 1) Shortening the antimicrobial prophylaxis, 2) Intestinal cleansing one day before the intervention by using enema, and 3) Using sterile gel (single patient use only) during biopsy. Patients were diagnosed as clinical or microbiologically confirmed healthcare-associated infection according to the 'Centers for Disease Control and Prevention' criteria. The preintervention period was 2007 July-December and the intervention period was 2008 January-July. Results: Overall infection/infectious complication rate (10.5% vs. 3.8%; p=0.007), overall clinically defined infection rate (4.8% vs. 1.1%; p=0.028) and overall microbiologically defined infection rate (5.8% vs. 2.7%; p=0.002) decreased significantly in the post intervention period. Conclusions: Our findings suggest that shorter antimicrobial prophylaxis regimens, using sterile gels and intestinal cleansing may be useful in the control of infections developing after TPB.en_US
dc.identifier.doi10.4274/mjima.2017.6
dc.identifier.issn2147-673X
dc.identifier.issn2147-673Xen_US
dc.identifier.urihttps://doi.org/10.4274/mjima.2017.6
dc.identifier.urihttps://hdl.handle.net/11454/32687
dc.identifier.volume6en_US
dc.identifier.wosWOS:000419992100006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofMediterranean Journal of Infection Microbes and Antimicrobialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntibiotic prophylaxisen_US
dc.subjectpostoperative complicationen_US
dc.subjectpreventionen_US
dc.subjectquinolonesen_US
dc.subjectesblen_US
dc.titleEffect of Shorter Antimicrobial Prophylaxis and Pre-Intervention Measures on Infections Developing After Transrectal Prostate Biopsiesen_US
dc.typeArticleen_US

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