The effect of radiotherapy on propylene glycol-induced cholesteatoma in rats

Küçük Resim Yok

Tarih

2008

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Mediterranean Soc Otology & Audiology

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

OBJECTIVE: Radiotherapy has been an alternative therapy in benign pathologies with epithelial and connective tissue hyperplasia. The aim of this study was to investigate the efficacy of low dose radiotherapy in the inhibition of cholesteatoma in an experimantal cholesteatoma model in rats. MATERIAL AND METHODS: Thirty-five Wistar albino rats were used to form 3 groups: Group I (n=20; bilateral cholesteatoma induction with propylene-glycol), Group 11 (n=10; unilateral cholesteatoma induction with propylene-glycol and unilateral intratympanic saline injection), Group III (n=5, control group without injection). The effect of radiotherapy was evaluated according to the histopathological parameters. RESULTS: The results indicated that low dose radiotherapy was ineffective in the management of cholesteatoma in this histopathological study.

Açıklama

Anahtar Kelimeler

Kaynak

Mediterranean Journal of Otology

WoS Q Değeri

N/A

Scopus Q Değeri

N/A

Cilt

4

Sayı

2

Künye