Enhanced biocompatibility of GPC by ion implantation and deposition

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dc.contributor.authorZimmerman, R.
dc.contributor.authorGuerhan, I.
dc.contributor.authorMuntele, C.
dc.contributor.authorIla, D.
dc.contributor.authorRodrigues, M.
dc.contributor.authorOezdal-Kurt, F.
dc.contributor.authorSen, B. H.
dc.date.accessioned2019-10-27T19:32:57Z
dc.date.available2019-10-27T19:32:57Z
dc.date.issued2007
dc.departmentEge Üniversitesien_US
dc.description14th International Conference on Surface Modification by Ion Beams (SMMIB 05) -- SEP 04-09, 2005 -- Kusadasi, TURKEYen_US
dc.description.abstractBiocompatible Glassy Polymeric Carbon (GPC) is used for artificial heart valves and in other biomedical applications. Although it is ideally suited for implants in the blood stream, tissue that normally forms around the moving parts of a GPC heart valve sometimes loses adhesion and creates embolisms downstream. We have previously shown that oxygen ion implantation slightly enhances cell adhesion to GPC. Here we compare silver ion implantation and silver deposition, each of which strongly inhibits cell attachment on GPC. Inhibition of cell adhesion is the more desirable improvement to current GPC cardiac implants. In vitro biocompatibility tests have been carried out with model cell lines to demonstrate that traces of silver can favorably influence the surface of GPC for biomedical applications. (c) 2007 Published by Elsevier B.V.en_US
dc.description.sponsorshipTUBITAK, Ege Univ, AKZ NOBEL KEMIPOL A S, ESBAS, HIPOKRAT A S, EYUP ALTAN, MEHMET ALTAN, MUSTAFA ALTAN, Off Naval Res Global, CemeCon Scandinavia, EBSO, Ford Otosan, Turk Otomobil Fabridasi, Egen Otomotiv Sanayi ve Ticaret A S, Kale Kahp Makina ve Kalp Sanayi A S, Canakkale Seramilk Kalevodur, Kale Grp, Ege Univ Sci & Technol Ctr, Mat Res Socen_US
dc.identifier.doi10.1016/j.surfcoat.2006.09.317
dc.identifier.endpage8023en_US
dc.identifier.issn0257-8972
dc.identifier.issn0257-8972en_US
dc.identifier.issue19-20en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage8020en_US
dc.identifier.urihttps://doi.org/10.1016/j.surfcoat.2006.09.317
dc.identifier.urihttps://hdl.handle.net/11454/39387
dc.identifier.volume201en_US
dc.identifier.wosWOS:000249034000005en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Saen_US
dc.relation.ispartofSurface & Coatings Technologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcarbon biocompatibilityen_US
dc.subjectcell adhesionen_US
dc.titleEnhanced biocompatibility of GPC by ion implantation and depositionen_US
dc.typeArticleen_US

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