Estrone specific molecularly imprinted polymeric nanospheres: Synthesis, characterization and applications for electrochemical sensor development

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dc.contributor.authorCongur G.
dc.contributor.authorSenay H.
dc.contributor.authorTurkcan C.
dc.contributor.authorCanavar E.
dc.contributor.authorErdem A.
dc.contributor.authorAkgol S.
dc.date.accessioned2019-10-27T08:23:25Z
dc.date.available2019-10-27T08:23:25Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractThe aim of this study is (i) to prepare estrone-imprinted nanospheres (nano-EST-MIPs) and (ii) to integrate them into the electrochemical sensor as a recognition layer. N-methacryloyl-(l)-phenylalanine (MAPA) was chosen as the complexing monomer. Firstly, estrone (EST) was complexed with MAPA and the EST-imprinted poly(2-hyroxyethylmethacrylate-co-N-methacryloyl-(l)- phenylalanine) [EST-imprinted poly(HEMA-MAPA)] nanospheres were synthesized by surfactant-free emulsion polymerization method. The specific surface area of the EST-imprinted poly(HEMA-MAPA) nanospheres was found to be 1275 m2/g with a size of 163.2 nm in diameter. According to the elemental analysis results, the nanospheres contained 95.3 mmole MAPA/g nanosphere. The application of EST specific MIP nanospheres for the development of an electrochemical biosensor was introduced for the first time in our study by using electrochemical impedance spectroscopy (EIS) technique. This nano-MIP based sensor presented a great specificity and selectivity for EST. © 2013 Bentham Science Publishers.en_US
dc.identifier.doi10.2174/1386207311316070001
dc.identifier.endpage510en_US
dc.identifier.issn1386-2073
dc.identifier.issn1386-2073en_US
dc.identifier.issue7en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage503en_US
dc.identifier.urihttps://doi.org/10.2174/1386207311316070001
dc.identifier.urihttps://hdl.handle.net/11454/26423
dc.identifier.volume16en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofCombinatorial Chemistry and High Throughput Screeningen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElectrochemical impedance spectroscopyen_US
dc.subjectElectrochemical sensoren_US
dc.subjectEstroneen_US
dc.subjectHEMA-MAPAen_US
dc.subjectMolecularly imprinted polymeren_US
dc.titleEstrone specific molecularly imprinted polymeric nanospheres: Synthesis, characterization and applications for electrochemical sensor developmenten_US
dc.typeArticleen_US

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