The effect of heart transplantation on mortality in end-stage heart failure patients with UNOS status 2 [UNOS 2 statüsündeki son dönem kalp yetersizligi hastalarinda kalp naklinin mortaliteye etkisi]

Basit Öğe Kaydı
dc.contributor.authorDuygu H.
dc.contributor.authorZoghi M.
dc.contributor.authorNalbantgil S.
dc.contributor.authorEngin Ç.
dc.contributor.authorYagdi T.
dc.contributor.authorAkilli A.
dc.contributor.authorAkin M.
dc.contributor.authorÖzbaran M.
dc.date.accessioned2019-10-27T00:01:41Z
dc.date.available2019-10-27T00:01:41Z
dc.date.issued2006
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectives: Despite recent developments in medical treatments and assist device applications, management strategies for end-stage heart failure patients with UNOS status 2 (United Network for Organ Sharing) are still controversial. We evaluated the clinical condition and prognosis of end-stage heart failure patients with UNOS status 2, who were placed on the waiting list for heart transplantation. Study design: The study included 78 patients (62 men, 16 women; mean age 43±12 years) with UNOS status 2. The patients were assessed in terms of frequency of hospitalization during waiting for transplantation, shift to a higher level of UNOS status, transplantations performed, and mortality. Results: The mean duration of waiting on the list was 17±10 months. The frequency of hospitalization due to heart failure was 4±2/year. An implantable cardioverter defibrillator was used in seven patients (9%) for persistent ventricular tachycardia. Nine patients (11.5%) shifted to UNOS status 1B. Eighteen patients (23.1%) underwent orthotopic heart transplantation following six months of waiting on the list. Mortality rates were 25% (n=15) and 22.2% (n=4) for patients on the waiting list and for transplant patients at the end of the first year of transplantation, respectively (p=0.03). The main cause of mortality was sudden cardiac death (73.3%, n=11) for patients on the transplantation list. There was a significant difference in terms of combined end-point of mortality and shift to UNOS status 1B between transplanted (n=24, 40%) and untransplanted (n=4, 22.2%) patients (p=0.01). Conclusion: Heart transplantation is an appropriate alternative for preventing impending clinical deterioration, frequent attacks of heart failure, and cardiac deaths in patients with UNOS status 2.en_US
dc.identifier.endpage483en_US
dc.identifier.issn1016-5169
dc.identifier.issn1016-5169en_US
dc.identifier.issue8en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage479en_US
dc.identifier.urihttps://hdl.handle.net/11454/21564
dc.identifier.volume34en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDeath, sudden/etiologyen_US
dc.subjectHeart failure, congestiveen_US
dc.subjectHeart transplantationen_US
dc.subjectPatient selectionen_US
dc.subjectWaiting listsen_US
dc.titleThe effect of heart transplantation on mortality in end-stage heart failure patients with UNOS status 2 [UNOS 2 statüsündeki son dönem kalp yetersizligi hastalarinda kalp naklinin mortaliteye etkisi]en_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu