(18)FDG conjugated magnetic nanoparticle probes: synthesis and in vitro investigations on MCF-7 breast cancer cells

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dc.contributor.authorOzkaya, Feriha
dc.contributor.authorUnak, Perihan
dc.contributor.authorMedine, E. Ilker
dc.contributor.authorSakarya, Serhan
dc.contributor.authorUnak, Gulcan
dc.contributor.authorTimur, Suna
dc.date.accessioned2019-10-27T21:52:55Z
dc.date.available2019-10-27T21:52:55Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstract(18)FDG conjugated magnetic iron oxide nanoparticles (MNPs) were synthesized as PET-MR hybrid imaging agent. Synthesized and characterized NPs were then applied to MCF-7 human breast cancer cells. (18)FDG conjugated MNPs exhibited the cell incorporation ratio up to 30 %. As well as the characterization studies, apoptotic effects were observed depending on the cellular incorporations by the time. In conclusion, synthesized structures could have a potential as hybrid imaging agent in PET-MR imaging systems besides apoptotic effect on cancer cells.en_US
dc.description.sponsorshipEge University Scientific Research FundEge University [2008 NBE 08, 2009 FEN 007]en_US
dc.description.sponsorshipThe authors thank to Ege University Scientific Research Fund for the financial support with the Project Numbers 2008 NBE 08 and 2009 FEN 007. Authors also thank to Adnan Menderes University Science Technology Research and Application Center for cell culture experiments.en_US
dc.identifier.doi10.1007/s10967-012-2248-2
dc.identifier.endpage1796en_US
dc.identifier.issn0236-5731
dc.identifier.issn0236-5731en_US
dc.identifier.issue3en_US
dc.identifier.startpage1789en_US
dc.identifier.urihttps://doi.org/10.1007/s10967-012-2248-2
dc.identifier.urihttps://hdl.handle.net/11454/47772
dc.identifier.volume295en_US
dc.identifier.wosWOS:000314895400026en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Radioanalytical and Nuclear Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectF-18en_US
dc.subjectMagnetite nanoparticlesen_US
dc.subjectMannose triflateen_US
dc.subjectApoptosisen_US
dc.subjectCancer diagnosisen_US
dc.title(18)FDG conjugated magnetic nanoparticle probes: synthesis and in vitro investigations on MCF-7 breast cancer cellsen_US
dc.typeArticleen_US

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