Encapsulated chlorhexidine digluconate usage on the diabetic footwear upper leathers
Küçük Resim Yok
Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
CSIR-CLRI
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
It is important for a therapeutic shoe to have a wearable quality and its comfortable use is also prominent in terms of providing an increase in user's quality of life. In long-term treatment of diseases, medical products which are to be manufactured with medical leather materials might be a prominent alternative via local effect application as an adjuvant to the treatment. It is aimed in this study to produce micro-particles which contain the active agent chlorhexidine digluconate and application of these micro-particles on upper leather for manufacturing diabetic shoes while providing them a functional quality. Within the scope of the project, micro-particles loaded with drugs were obtained via spraying chlorhexidine digluconate active agent and through spraying with ethyl cellulose polymer and ustulation. In vitro characterisation studies were performed on the acquired microparticles. Additionally, active agent quantitation and in vitro drug delivery studies were also performed. Following the studies, the determined optimum microparticle formulations were applied on the leather, then existence and efficiency of microparticles within the leather was shown in the subsequent studies.
Açıklama
34th International Union of Leather Technologists and Chemist Societies Congress, IULTCS 2017 -- 5 February 2017 through 8 February 2017 -- 133186
Anahtar Kelimeler
Chlorhexidine digluconate, Diabetic shoes, Encapsulation, Upper leather
Kaynak
Proceedings of the 34th IULTCS Congress: Science and Technology for Sustainability of Leather
WoS Q Değeri
Scopus Q Değeri
N/A
