FLAVONOID CONTENTS ANTIOXIDANT AND NEUROPROTECTIVE ACTIVITIES OF CRATAEGUS MONOGYNA JACQ. LEAVES AND FLOWERS

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dc.authoridAktar Kiremitci, Selin/0000-0001-8618-2682
dc.authorwosidAktar Kiremitci, Selin/AGI-6627-2022
dc.contributor.authorCebe, Gozde Elgin
dc.contributor.authorKiremitci, Selin Aktar
dc.contributor.authorErdogan, M. Alper
dc.contributor.authorKonyalioglu, Sibel
dc.contributor.authorYengin, Cigdem
dc.contributor.authorDer, Gulay
dc.contributor.authorKilinc, Emrah
dc.date.accessioned2023-01-12T20:19:22Z
dc.date.available2023-01-12T20:19:22Z
dc.date.issued2021
dc.departmentN/A/Departmenten_US
dc.description.abstractAntioxidant activities of Crataegus species' leaves and fruits so far have been reported in literature, however, several factors ranging from plant part(s), harvest season, the species and the geographical origin of the plant extensively impede and influence these antioxidant activities. In this research, ethanolic extracts of leaves and flowers of Crataegus monogyna Jacq. (CRT) collected from 6 different locations (Karaman, Bolu, Sinop, Egirdir, Elbistan, Seydisehir: CRT-1 to CRT-6) between May and June 2018 were evaluated for their flavonoid contents, antioxidant (RSA and PRAP assays) and neuroprotective capacities (SHSY5Y). Content of flavonoids epicatechin and hyperoside detected using HPLC is reported. Both CRT-3 and CRT-4 are remarkable in cycles of flavonoid content, antioxidant, and neuroprotective activities. Results show that leaves and flowers of C. monogyna provide considerable antioxidant protection and neuroprotective activity and can be a suitable raw material for medicine, food, and cosmetic industries.en_US
dc.description.sponsorshipEge University Department of Scientific Research Projects (BAP) [2014-TIP-086, 18/ECZ/006, 16/ECZ/022]; Ministry of Forestry Project [15.7701]en_US
dc.description.sponsorshipAuthors would like to thank Prof. Dr. A. Ulvi ZEYBEK and Prof. Dr. Bayram YILDIZ for the donation and identification of the plant materials used. Many thanks to Prof. Dr. Raul Enriquez HABIB for his technical support. This study was financially backed up by Ege University Department of Scientific Research Projects (BAP, Project numbers: 2014-TIP-086, 18/ECZ/006 and 16/ECZ/022) and Ministry of Forestry Project (15.7701) partially.en_US
dc.identifier.endpage10514en_US
dc.identifier.issn1018-4619
dc.identifier.issn1610-2304
dc.identifier.issn1018-4619en_US
dc.identifier.issn1610-2304en_US
dc.identifier.issue9en_US
dc.identifier.startpage10505en_US
dc.identifier.urihttps://hdl.handle.net/11454/79106
dc.identifier.volume30en_US
dc.identifier.wosWOS:000691849600011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherParlar Scientific Publications (P S P)en_US
dc.relation.ispartofFresenius Environmental Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidanten_US
dc.subjectCrataegus monogynaen_US
dc.subjectHPLCen_US
dc.subjectNeuroprotectiveen_US
dc.subjectExtract Ws(R) 1442en_US
dc.subjectPolymeric Procyanidinsen_US
dc.subjectPhenolic-Compoundsen_US
dc.subjectHawthornen_US
dc.subjectFruiten_US
dc.subjectSpp.en_US
dc.subjectPinnatifidaen_US
dc.subjectCapacityen_US
dc.subjectIdentificationen_US
dc.subjectPharmacologyen_US
dc.titleFLAVONOID CONTENTS ANTIOXIDANT AND NEUROPROTECTIVE ACTIVITIES OF CRATAEGUS MONOGYNA JACQ. LEAVES AND FLOWERSen_US
dc.typeArticleen_US

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