Thioguanine-Related Chronic Hepatotoxicity in a Child with Acute Myeloid Leukemia: A Case Report and Review
dc.contributor.author | Karapinar, Tuba Hilkay | |
dc.contributor.author | Oymak, Yesim | |
dc.contributor.author | Ecevit, Cigdem | |
dc.contributor.author | Yilmaz, Funda | |
dc.contributor.author | Karakoyun, Miray | |
dc.contributor.author | Ay, Yilmaz | |
dc.contributor.author | Vergin, Canan | |
dc.date.accessioned | 2019-10-27T20:25:11Z | |
dc.date.available | 2019-10-27T20:25:11Z | |
dc.date.issued | 2015 | |
dc.department | Ege Üniversitesi | en_US |
dc.description.abstract | The association between 6-Thioguanine (6-TG) treatment and drug-induced liver injury has been reported since 1976. Recent reports have suggested that treatment of patients with 6-TG can lead to chronic hepatotoxicity and portal hypertension. Most of the cases reported to have 6-TG related hepatotoxicity had acute lymphoblastic leukemia or inflammatory bowel disease. In this case report, we discussed the diagnosis and approach in an acute myeloid leukemia patient who developed 6-TG related chronic hepatotoxicity. | en_US |
dc.identifier.doi | 10.4274/jpr.69885 | |
dc.identifier.endpage | 104 | en_US |
dc.identifier.issn | 2147-9445 | |
dc.identifier.issn | 2147-9445 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 102 | en_US |
dc.identifier.uri | https://doi.org/10.4274/jpr.69885 | |
dc.identifier.uri | https://hdl.handle.net/11454/42207 | |
dc.identifier.volume | 2 | en_US |
dc.identifier.wos | WOS:000219056100012 | en_US |
dc.identifier.wosquality | N/A | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.language.iso | tr | en_US |
dc.publisher | Galenos Yayincilik | en_US |
dc.relation.ispartof | Journal of Pediatric Research | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | 6-Thioguanine | en_US |
dc.subject | hepatotoxicity | en_US |
dc.subject | leukemia | en_US |
dc.title | Thioguanine-Related Chronic Hepatotoxicity in a Child with Acute Myeloid Leukemia: A Case Report and Review | en_US |
dc.type | Article | en_US |