Asthma-like symptomcystic fibrosis asthma?

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dc.authoridKartal Öztürk, Gökçen/0000-0002-0793-9710
dc.authorscopusid57214935988
dc.authorscopusid57211344435
dc.authorscopusid7004473191
dc.authorscopusid9036191300
dc.authorwosidKartal Öztürk, Gökçen/AAM-9743-2021
dc.contributor.authorOzturk, Gokcen Kartal
dc.contributor.authorEski, Aykut
dc.contributor.authorDemir, Esen
dc.contributor.authorGulen, Figen
dc.date.accessioned2023-01-12T20:19:06Z
dc.date.available2023-01-12T20:19:06Z
dc.date.issued2021
dc.departmentN/A/Departmenten_US
dc.description.abstractIntroduction: The diagnosis of asthma is still a difficult problem in cystic fibrosis. There is no consensus on how to define CF asthma. The aim of this study was to determine the role of bronchodilator response and laboratory evidence of allergy in CF asthma. Materials and Methods: Patients aged 6 years with evaluated bronchodilator response and characteristics of atopy were included in the study. Patients diagnosed with Allergic Bronchopulmonary Aspergillosis or pulmonary exacerbation were excluded. Results: A total of 204 CF patients were evaluated, and 40 who met the criteria were included. Asthma had been diagnosed in ten patients. A positive bronchodilator response was present in 47.3% of the patients tested. Aeroallergen sensitization was present in 52.5% of the patients. While the frequency of recurrent/history of wheezing, family history of atopy and elevated total immunoglobulin E were similar (p> 0.05), the frequencies of inhaled medication use and coexistence of asthma were statistically higher in the group with positive allergen sensitization (p< 0.05). The frequencies of positive bronchodilator response (77.7% versus 37.9%) and a family history of asthma/atopy (40% versus. 23%) were found to be similar in CF asthma and Cf. There were significant increases in total IgE and allergen-specific IgE and an increase in the frequency of aeroallergen sensitization in CF asthma compared to CF (p< 0.05). Conclusion: Although not routinely used in the evaluation of patients, allergen specific-IgE and skin prick test for aeroallergen sensitization may be used as an adjunctive test in patients with suspected clinical findings. The recognition of CF asthma may facilitate the development of targeted therapies.en_US
dc.identifier.doi10.5578/tt.20219806
dc.identifier.endpage176en_US
dc.identifier.issn0494-1373
dc.identifier.issn0494-1373en_US
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85111418268en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage167en_US
dc.identifier.urihttps://doi.org/10.5578/tt.20219806
dc.identifier.urihttps://hdl.handle.net/11454/79026
dc.identifier.volume69en_US
dc.identifier.wosWOS:000670437700005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTurkish Assoc Tuberculosis & Thoraxen_US
dc.relation.ispartofTuberkuloz Ve Toraks-Tuberculosis And Thoraxen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCystic fibrosisen_US
dc.subjectasthmaen_US
dc.subjectbronchodilator responsivenessen_US
dc.subjectatopyen_US
dc.subjectAllergic Bronchopulmonary Aspergillosisen_US
dc.subjectReversible Airway-Obstructionen_US
dc.subjectCystic-Fibrosisen_US
dc.subjectBronchodilatorsen_US
dc.subjectChildrenen_US
dc.subjectResponsivenessen_US
dc.subjectExerciseen_US
dc.titleAsthma-like symptomcystic fibrosis asthma?en_US
dc.title.alternativeAstım benzeri semptom mu veya “kistik fibrozis astım” mı?en_US
dc.typeArticleen_US

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