Investigation of nanoformulation and incorporation potential of radiolabeled curcumin using HeLa and MDAH-2774 cells
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Nowadays plant origin compounds with anti-cancer properties come into prominence, among them is curcumin (CUR) with a remarkable anti-cancer activity against various cancers. CUR was nanoformulated (CUR-PLGA) by the polymer based poly(lactic-co-glycolic acid) (PLGA) and both CUR and CUR-PLGA were radiolabeled with iodine-131 radionuclide for investigation of their in vitro behaviour on Human cervix adenocarcinoma (HeLa) and Ovarian endometrioid adenocarcinoma (MDAH-2774) cell lines. The newly described radiolabeled CUR and CUR-PLGA may be initiative discovery of novel potential imaging and therapeutic agents.
Açıklama
Anahtar Kelimeler
Curcumin (CUR), Poly(lactic-co-glycolic acid) (PLGA), Encapsulation, Radiolabeling, Iodine-131 (I-131), Cervical and ovarian cancer cell lines
Kaynak
Journal of Radioanalytical and Nuclear Chemistry
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
327
Sayı
1
