Breath as the mirror of our body is the answer really blowing in the wind? Recent technologies in exhaled breath analysis systems as non-invasive sensing platforms

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dc.authoridTimur, Suna/0000-0002-1981-7577
dc.authoridsalama, khaled Nabil/0000-0001-7742-1282
dc.authoridBALABAN HANOGLU, Simge/0000-0002-4540-1882
dc.authoridDurmus, Ceren/0000-0002-8648-0505
dc.authoridBeduk, Tutku/0000-0001-7365-6404
dc.authoridBeduk, Duygu/0000-0002-5394-4967
dc.authorscopusid57205630119
dc.authorscopusid57210729367
dc.authorscopusid57224479557
dc.authorscopusid57224474138
dc.authorscopusid57203414946
dc.authorscopusid6507577336
dc.authorscopusid8429335700
dc.authorwosidTimur, Suna/CAG-0914-2022
dc.authorwosidsalama, khaled Nabil/K-3689-2019
dc.contributor.authorBeduk, Tutku
dc.contributor.authorDurmus, Ceren
dc.contributor.authorHanoglu, Simge Balaban
dc.contributor.authorBeduk, Duygu
dc.contributor.authorSalama, Khaled Nabil
dc.contributor.authorGoksel, Tuncay
dc.contributor.authorTurhan, Kutsal
dc.date.accessioned2023-01-12T19:58:26Z
dc.date.available2023-01-12T19:58:26Z
dc.date.issued2021
dc.departmentN/A/Departmenten_US
dc.description.abstractHealth care monitoring is an enormous field of research that has great potential to solve many problems in human life. In recent years, non-invasive health monitoring has become a prerequisite for early diagnosis of various diseases such as lung cancer, oxidative stress, diabetes, to enable the prompt treatment and screening of crucial chemicals. Although analyzing of exhaled breath has been correlated with advanced analytical techniques such as gas chromatography and infrared spectroscopy, breath analyzing biosensing systems offer a cost-effective, sensitive platform for a straightforward analysis. However, current non-invasive sensing strategies have been lacking in practicality in terms of the design and usage, on-site ability and accessibility. This review will critically discuss current commercialized breath analyzers, the recent achievements for the use of the detection towards chemical and biological substances from exhaled breath as non-invasive sensing systems including challenges/drawbacks by addressing the practical applications and concerns in the field. The different fabrication strategies, methodology of detection techniques involved in the development of the breath analyzing systems will be overviewed and discussed along with the future opportunities for possible point of care applications with smartphone integration in this review. The scientific and technological challenges in the field are discussed in the conclusion. (C) 2021 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipEge University, Turkey; King Abdullah University of Science and Technology (KAUST), Saudi Arabiaen_US
dc.description.sponsorshipThe authors would like to thank Dr. Abdellatif Ait Lachen and Dr Veerappan Mani for their suggestions and comments. In addition, the authors would like to express their acknowledgments to the financial support of funding from Ege University, Turkey and King Abdullah University of Science and Technology (KAUST), Saudi Arabia.en_US
dc.identifier.doi10.1016/j.trac.2021.116329
dc.identifier.issn0165-9936
dc.identifier.issn1879-3142
dc.identifier.issn0165-9936en_US
dc.identifier.issn1879-3142en_US
dc.identifier.scopus2-s2.0-85107645754en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.trac.2021.116329
dc.identifier.urihttps://hdl.handle.net/11454/76903
dc.identifier.volume143en_US
dc.identifier.wosWOS:000711411900001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofTrac-Trends In Analytical Chemistryen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBreath analysisen_US
dc.subjectOn-site detectionen_US
dc.subjectNon-invasive diagnosticsen_US
dc.subjectPoint-of-Care (POC) diagnosticsen_US
dc.subjectSmartphone technologyen_US
dc.subjectBiomarkersen_US
dc.subjectAlcohol-Dehydrogenaseen_US
dc.subjectAcetoneen_US
dc.subjectBiomarkersen_US
dc.subjectEthanolen_US
dc.subjectSensorsen_US
dc.subjectIsopropanolen_US
dc.subjectElectrodesen_US
dc.subjectDiagnosisen_US
dc.titleBreath as the mirror of our body is the answer really blowing in the wind? Recent technologies in exhaled breath analysis systems as non-invasive sensing platformsen_US
dc.typeReviewen_US

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