The value of S100B protein measurement for the differential diagnosis of acute ischemic stroke in the geriatric population [Geriatrik hasta grubunda akut iskemik inme ayirici tanisinda S-100B protein ölçümünün degeri]

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dc.contributor.authorUncu A.
dc.contributor.authorKabaroglu C.
dc.contributor.authorBaşol G.
dc.contributor.authorBarutçuoglu B.
dc.contributor.authorUncu G.
dc.contributor.authorKumral E.
dc.contributor.authorBayindir O.
dc.date.accessioned2019-10-26T21:41:20Z
dc.date.available2019-10-26T21:41:20Z
dc.date.issued2012
dc.departmentEge Üniversitesien_US
dc.description.abstractIntroduction: A blood test supporting the clinical and radiological findings used for the diagnosis of acute ischemic stroke (AIS) is needed in the geriatric population. The aim was to demonstrate the value of S100B levels for the differential diagnosis of AIS. Materials and Method: 55 patients who have been diagnosed with AIS after admittance to an emergency room and 20 patients with transient ischemic attack (TIA) were enrolled. AIS diagnosis was based on a neurology consultation in agreement with laboratory and radiological findings. S100B levels were determined in fasting venous blood samples by an ELISA method. The results were expressed as median (minimum-maximum). Results: S100B levels were significantly higher in the AIS group [63.86 (50-1876) pg/ml] than the TIA group [50.14 (< 50- 87.63) pg/ml] (p= 0.001). S100B concentrations were not influenced by age, gender, body mass index or by the presence of coronary artery disease, diabetes mellitus, hyperlipidemia, cardiac arrhythmia, peripheral vascular disease, family history or cigarette smoking. The ROC analysis demonstrated that the area under the curve was 0.836 (p= 0.0001). Conclusion: S100B measurement is a rapid, simple and cost-effective analysis which may be used for the differential diagnosis of AIS in the early stages, especially in emergency and intensive care settings.en_US
dc.identifier.endpage384en_US
dc.identifier.issn1304-2947
dc.identifier.issn1304-2947en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage378en_US
dc.identifier.urihttps://hdl.handle.net/11454/18290
dc.identifier.volume15en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofTurk Geriatri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIschemic attacken_US
dc.subjectS100 proteinsen_US
dc.subjectStrokeen_US
dc.subjectTransienten_US
dc.titleThe value of S100B protein measurement for the differential diagnosis of acute ischemic stroke in the geriatric population [Geriatrik hasta grubunda akut iskemik inme ayirici tanisinda S-100B protein ölçümünün degeri]en_US
dc.typeArticleen_US

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