Phototransformations of (+)-tazettine
Küçük Resim Yok
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The sunlight irradiation of a methanolic solution of (+)-tazettine afforded a series of alkaloidal and nonalkaloidal photolysis products, the structures of five of which were elucidated by spectral analysis, including 2D NMR experiments. N-methylcrinasiadine and trisphaeridine, two already known Amaryllidaceae alkaloids, result from the photoconversion of the tazettine skeleton into the phenanthridine nucleus. 11-Oxo-N-formyl-3,4-dihydro-N-norgraciline and 11, 12-dioxo-3,4-dihydro-N-norgraciline reveal that the tazettine nucleus undergoes a conversion to form the more recently established subgroup of Amaryllidaceae alkaloids, the gracilines. The fifth compound retains the tazettine nucleus, but C-6 is oxidized to form a five membered lactam. Thus, this compound is properly named as 6-oxotazettine.
Açıklama
Anahtar Kelimeler
(+)-tazettine, 3,4-dihydrograciline, 6-oxotazettine, Amaryllidaceae alkaloids, Phenanthridine alkaloids, Phototransformation
Kaynak
Journal of Pharmacy of Istanbul University
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
38
Sayı
1
