Search for antifungal compounds from some Verbascum species growing in Turkey
Küçük Resim Yok
Tarih
2004
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Turkish medicinal plants provide a rich source of biologically-active natural products. With the use of simple bioassays, it is possible to evaluate the bioactivity of the natural compounds. Antifungal screening of 16 compounds in a matrix format from two Verbascum species growing in Turkey was conducted directly on thin-layer chromatographic (TLC) plates sprayed with a spore suspension. Compounds possessing strong antifungal activity produced a clear zone of inhibition bounded by a sharp margin regardless of the size of the inhibitory zone. Ilwensisaponin A and C from Verbascum pterocalycinum var. mutense Hub.-Mor. were found to be active. Bioautographic assay indicated that the saponins appeared to be the most effective against Colletotrichum acutatum, C. fragariae and C. gloeosporioides.
Açıklama
Anahtar Kelimeler
Antifungal Activity, Bioactive Compounds, Ilwensisaponin A, Ilwensisaponin C, Medicinal plants, Saponins, Scrophulariaceae, Verbascum lasianthum, Verbascum pterocalycinum var. mutense
Kaynak
Fabad Journal of Pharmaceutical Sciences
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
28
Sayı
3
