Prenatal diagnosis of caudal regression syndrome without maternal diabetes mellitus [maternal diabetes mellitusun eşlik etmedigi kaudal regresyon sendromunun prenatal tani{dotless}si{dotless}]

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dc.contributor.authorYeniel A.O.
dc.contributor.authorErgenoglu A.M.
dc.contributor.authorSagol S.
dc.date.accessioned2019-10-26T22:00:10Z
dc.date.available2019-10-26T22:00:10Z
dc.date.issued2011
dc.departmentEge Üniversitesien_US
dc.description.abstractCaudal regression syndrome is a rare congenital malformation with varying degrees of early gestational developmental failure. It is also known as sacral agenesis or caudal dysplasia. The cause of this malformation is thought to be defects in neuralization around the 28th day of the gestational period. Although maternal uncontrolled diabetes, genetic predisposition and vascular hypoperfusion are the possible risk factors, actual pathogenesis is unclear. CRS is generally diagnosed at prenatal assessment, but also a varying number of new-borns with some degree of anomaly may be presented. In our case, we diagnosed a caudal regression syndrome fetus early in the second trimester. Determination of the pathology early in the gestational age gives parents a chance for termination of pregnancy. Although diabetes mellitus is the major risk factor for CRS, as in our case, sporadic presentations may occur. So clinicians should consider CRS when CRL is shorter than expected and incomplete vertebral ossification is observed both in gray scala and 3D imaging ultrasonography. © 2011 by the Turkish-German Gynecological Education and Research Foundation.en_US
dc.identifier.doi10.5152/jtgga.2011.43
dc.identifier.endpage188en_US
dc.identifier.issn1309-0399
dc.identifier.issn1309-0399en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage186en_US
dc.identifier.urihttps://doi.org/10.5152/jtgga.2011.43
dc.identifier.urihttps://hdl.handle.net/11454/19186
dc.identifier.volume12en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofJournal of the Turkish German Gynecology Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject3D ultrasonographyen_US
dc.subjectCaudal regression syndromeen_US
dc.subjectDiabetes mellitusen_US
dc.subjectSirenomeliaen_US
dc.subjectVertebral anomalyen_US
dc.titlePrenatal diagnosis of caudal regression syndrome without maternal diabetes mellitus [maternal diabetes mellitusun eşlik etmedigi kaudal regresyon sendromunun prenatal tani{dotless}si{dotless}]en_US
dc.typeArticleen_US

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