Esmolol, remifentanly and esmolol+remifentanyl combinations effects on hemodynamic changes caused by laryngoscopy and tracheal intubation [Laringoskopi ve trakeal entübasyona bagli hemodinamik degişiklikler üzerine esmolol, remifentanil ve esmolol+remifentanil kombinasyonunun etkileri]

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dc.contributor.authorAltunişik U.
dc.contributor.authorKaraman S.
dc.contributor.authorGünüşen I.
dc.contributor.authorFirat V.
dc.date.accessioned2019-10-26T23:59:37Z
dc.date.available2019-10-26T23:59:37Z
dc.date.issued2007
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: The efficacy of esmolol, remifentanil and esmolol+remifentanil on changes in heart rate (HR) and arterial blood pressure (ABP) after laryngoscopy and tracheal intubation were compared. Materials and Methods: Sixty patients (ASAI-II) were included in this study. Before induction HR, systolic and diastolic arterial pressure (SAP and DAP), mean arterial pressure (MAP) and Rate-Pressure Product (RPP: HRxSAP) values were measured three times with 1 minute intervals and the mean value of these measurements was accepted as baseline. Patients were divided into three groups, Group ESM (esmolol group) received 2 mg kg-1 esmolol IV, Group REM (remifentanil group) 1 µg kg-1 remifentanil IV, while Group ESM+REM (esmolol+remifentanil group) received the combination of 1 mg kg-1 esmolol + 0.5 µg kg-1 remifentanil IV. Before induction and intubation and through the 1. to 10. minute after intubation HR, SAP, DAP, MAP was recorded with 1 minute intervals and RPP was calculated according to this data. Results: There was no difference between the groups when demographic data HR, SAP, DAP, MAP and RPP values were compared, but in all groups the HR values were significantly higher at the 1. minute after intubation in comparison with preintubation values. In the remifentanil group measurements showed a significant increase in HR at the 1. minute after intubation when compared to baseline and preinduction measurements. RPP was higher at the 1. minute after intubation in all groups when compared with preintubation values, while the SAP, DAP, and MAP values significantly increased only in esmolol and remifentanil groups (p<0.05). Conclusion: We concluded that, esmolol and esmolol+remifentanil were more effective than remifentanil in preventing hemodynamic response to laryngoscopy and intubation.en_US
dc.identifier.endpage168en_US
dc.identifier.issn1304-0871
dc.identifier.issn1304-0871en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage163en_US
dc.identifier.urihttps://hdl.handle.net/11454/21426
dc.identifier.volume35en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyon Dernegi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEsmololen_US
dc.subjectHemodynamic responseen_US
dc.subjectIntubationen_US
dc.subjectLaryngoscopyen_US
dc.subjectRemifentanilen_US
dc.titleEsmolol, remifentanly and esmolol+remifentanyl combinations effects on hemodynamic changes caused by laryngoscopy and tracheal intubation [Laringoskopi ve trakeal entübasyona bagli hemodinamik degişiklikler üzerine esmolol, remifentanil ve esmolol+remifentanil kombinasyonunun etkileri]en_US
dc.typeArticleen_US

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