Aptasensors for Small Molecule Detection

Basit Öğe Kaydı
dc.contributor.authorWalter, Johanna-Gabriela
dc.contributor.authorHeilkenbrinker, Alexandra
dc.contributor.authorAusterjost, Jonas
dc.contributor.authorTimur, Suna
dc.contributor.authorStahl, Frank
dc.contributor.authorScheper, Thomas
dc.date.accessioned2019-10-27T21:41:00Z
dc.date.available2019-10-27T21:41:00Z
dc.date.issued2012
dc.departmentEge Üniversitesien_US
dc.description.abstractAptamers are single-stranded oligonucleotides composed of RNA or DNA that are able to bind their corresponding targets via molecular recognition. Thus, aptamers can be thought of as nucleic acid-based alternatives to antibodies and have attracted attention as receptors in biosensors. Aptamers seem to be ideal biological recognition elements, since they enable the design of intelligent sensors based on their specific properties. Especially the fact that most aptamers undergo conformational changes during the binding of the target and their oligonucleotide nature can be used to rationally design novel sensing strategies. This review focuses on aptasensors for the detection of small molecules. In the first part, aptamers, their generation and their properties are briefly described. In the second part, different design strategies for aptasensors are reviewed, and examples for the detection of small molecules are given.en_US
dc.identifier.doi10.5560/ZNB.2012-0147
dc.identifier.endpage986en_US
dc.identifier.issn0932-0776
dc.identifier.issn0932-0776en_US
dc.identifier.issue10en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage976en_US
dc.identifier.urihttps://doi.org/10.5560/ZNB.2012-0147
dc.identifier.urihttps://hdl.handle.net/11454/46498
dc.identifier.volume67en_US
dc.identifier.wosWOS:000312119500003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherVerlag Z Naturforschen_US
dc.relation.ispartofZeitschrift Fur Naturforschung Section B-A Journal of Chemical Sciencesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSmall Moleculeen_US
dc.subjectAptameren_US
dc.subjectBiosensoren_US
dc.subjectAptasensoren_US
dc.titleAptasensors for Small Molecule Detectionen_US
dc.typeReview Articleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu