Use of radiopharmaceuticals for imaging hypoxic tissues [Hipoksik dokularin görüntülenmesinde radyofarmasötiklerin klinik kullanimi]
Küçük Resim Yok
Tarih
2001
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Hypoxia is the state between oxygen absence and normal oxygenation of the healthy tissue and when the oxygen necessity for normal cell function goes beyond the sources, cells respond to this situation by down-regulating their metabolism. This hypoxic condition is observed in various clinically significant diseases primarily cancer. Tumor hypoxia may increase resistance to radiation therapy and to some forms of chemotherapy. That is why detection of hypoxia is important. Radiolabelled nitroimidazoles, misonidazole analogues, iodoazomycin nucleosides are used for imaging hypoxia.
Açıklama
Anahtar Kelimeler
Hypoxia, Imaging, Radiopharmaceuticals
Kaynak
Fabad Journal of Pharmaceutical Sciences
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
26
Sayı
2
