Alterations of serum parathormone, calcium, and Vitamin D levels in end-stage heart failure cases performed with left ventricular assist device implantation [Sol ventrikül destek cihazi implantasyonu uygulanan son dönem kalp yetmezlikli olgularda serum parathormon, kalsiyum ve Vitamin D seviyelerindeki de?işim]

Basit Öğe Kaydı
dc.contributor.authorÖztürk P.
dc.contributor.authorKirazli Y.
dc.date.accessioned2021-05-03T20:48:02Z
dc.date.available2021-05-03T20:48:02Z
dc.date.issued2018
dc.description.abstractObjective: Determination of the osteoporosis susceptibility in end-stage heart failure (ESHF) cases who underwent left ventricular assist device (LVAD) implantation by examining the alterations of serum parathormone (PTH), calcium, and Vitamin D levels. Materials and Methods: Records of 375 patients who underwent continuous-flow LVAD implantation with diagnosis of ESHF in our clinic were retrospectively scanned. Thirty three patients with a minimum three months of follow-up, who had complete data about serum PTH, calcium, 25-hydroxyvitamin-D (25-OH-D), and pro-brain natriuretic peptide (pro-BNP) levels for pre and postoperative periods, as well as those with a bone mineral density (BMD) measurement were included in the study. In cases whose bone mineral density measurements made for lomber and hip region, for parameters that were worked with demographic data, initial and last follow-up serum values were recorded and statistical changes were examined. Furthermore, the effects of implanted LVAD type on the studied parameters were evaluated comparatively. Results: Totally 33 cases, four of female (12.1%), mean age and body mass index were found 52.7±12.0 years and 27.3±4.3 kg/m2. Postoperative BMD examinations revealed that 50% of cases osteoporosis and 35.7% of osteopenia. Preoperative serum PTH, calcium, 25-OH-D, osteocalcin, urea, creatinine, glomerular filtration rate, and pro-BNP concentrations were 100.9±39.5 pg/mL, 8.9±0.8 mg/dL, 26.7±17.4 ng/mL, 6.98±5.46 ng/mL, 80.2±57.9 mg/dL, 1.48±0.89 mg/dL, 52.99±13.32 mL/minute/1.73 m2, and 9348.7±8176.7 pg/mL; whereas, at the end of the mean follow-up period of 14.2±7.7 months, these values were determined as 78.3±26.3 pg/mL, 9.2±0.5 mg/ dL, 29.8±13.8 ng/mL, 7.55±3.14 ng/mL, 36.2±17.2 mg/dL, 0.98±0.26 mg/dL, 59.72±1.21 mL/minute/1.73 m2, and 1838.9±1853.2 pg/ mL, respectively (p<0.001, p=0.033, p=0.038, p=0.841, p<0.001, p=0.003, p=0.006, and p<0.001, respectively). There was no statistically significant difference when the cases of two different LVAD type implanted were compared in terms of changes in study parameters. Conclusion: Close control of calcium, 25-OH-D, and PTH serum levels is necessary in patients with ESHF underwent with left ventricular assist device; regarding those who have osteoporosis or osteopenia according to BMD measurements except the daily calcium-rich dietary advice, the regulation of medical treatment should be planned. © Telif Hakki 2018 Türkiye Osteoporoz Derne?i.en_US
dc.identifier.doi10.4274/tod.32659
dc.identifier.endpage10en_US
dc.identifier.issn2146-3816
dc.identifier.issn2146-3816en_US
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85051554200en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage5en_US
dc.identifier.urihttps://doi.org/10.4274/tod.32659
dc.identifier.urihttps://hdl.handle.net/11454/70711
dc.identifier.volume24en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherGalenos Yayincilik,en_US
dc.relation.ispartofTurk Osteoporoz Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHeart failureen_US
dc.subjectLeft ventricular assist deviceen_US
dc.subjectOsteoporosisen_US
dc.titleAlterations of serum parathormone, calcium, and Vitamin D levels in end-stage heart failure cases performed with left ventricular assist device implantation [Sol ventrikül destek cihazi implantasyonu uygulanan son dönem kalp yetmezlikli olgularda serum parathormon, kalsiyum ve Vitamin D seviyelerindeki de?işim]en_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu