Molecularly Imprinted Polypyrrole for DNA Determination

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dc.contributor.authorRatautaite, Vilma
dc.contributor.authorTopkaya, Seda Nur
dc.contributor.authorMikoliunaite, Lina
dc.contributor.authorOzsoz, Mehmet
dc.contributor.authorOztekin, Yasemin
dc.contributor.authorRamanaviciene, Almira
dc.contributor.authorRamanavicius, Arunas
dc.date.accessioned2019-10-27T21:52:15Z
dc.date.available2019-10-27T21:52:15Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractIn this study graphite electrodes modified by a thin DNA-imprinted polypyrrole layer, which was able to bind specific target-DNA, are reported. For this aim, electrochemical synthesis of polypyrrole was performed on a pencil graphite electrode by cyclic voltammetry (CV) or by potential pulse sequences (PPS). The modified electrode surface was used for electrochemical determination of target-DNA by differential pulse voltammetry. According to our best knowledge this is a first report on the application of DNA-imprinted polymer for the determination of target-DNA. The results showed that the molecularly imprinted polypyrrole (MIPPy) layer that formed on the carbon electrode surface was sensitive for target-DNA, while the nonimprinted polypyrrole layer was not sensitive to the same target-DNA. Comparison of electrodes modified using PPS and CV techniques is presented.en_US
dc.description.sponsorshipEuropean UnionEuropean Union (EU) [VP1-3.1-SMM-01]en_US
dc.description.sponsorshipFinancial support from postdoctoral fellowship funded by the European Union Structural Funds Project "Postdoctoral Fellowship Implementation in Lithuania" within the framework of the Measure for Enhancing Mobility of Scholars and Other Researchers and the Promotion of Student Research (VP1-3.1-SMM-01) of the Program of Human Resources Development Action Plan is acknowledged.en_US
dc.identifier.doi10.1002/elan.201300063
dc.identifier.endpage1177en_US
dc.identifier.issn1040-0397
dc.identifier.issn1521-4109
dc.identifier.issn1040-0397en_US
dc.identifier.issn1521-4109en_US
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1169en_US
dc.identifier.urihttps://doi.org/10.1002/elan.201300063
dc.identifier.urihttps://hdl.handle.net/11454/47560
dc.identifier.volume25en_US
dc.identifier.wosWOS:000318798000011en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofElectroanalysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMolecularly imprinted polymers (MIPs)en_US
dc.subjectPolypyrroleen_US
dc.subjectDNAen_US
dc.subjectElectrochemical DNA biosensoren_US
dc.subjectDNA-imprinted polymeren_US
dc.titleMolecularly Imprinted Polypyrrole for DNA Determinationen_US
dc.typeArticleen_US

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