Effects of two different doses of dexmedetomidine on intraoperative desflurane consumption, hemodynamic parameters and neuromuscular blockade [İki farkli deksmedetomidin dozunun i·ntraoperatif desfluran tüketimi, hemodinamik parametreler ve kas gevşemesi üzerine olan etkileri]

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dc.contributor.authorAliyeva A.
dc.contributor.authorGünüşen I.
dc.contributor.authorKaraman S.
dc.contributor.authorFirat V.
dc.date.accessioned2019-10-26T22:53:28Z
dc.date.available2019-10-26T22:53:28Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose: The effects of two different doses of dexmedetomidine, a selective ? 2-receptor agonist, on anesthetic agent consumption and neuromuscular blockade and intraoperative analgesic requirement were aimed to compare with the control group. Material and methods: Sixty patients between 18 and 60 ages were studied. Three groups were made, dexmedetomidine infusion was begun for Group A and Group B, 1 µg kg -1 and 0.5 µg kg -1 respectively and Group C were infused serum physiologic. After the standard anesthesia induction, dexmedetomidine infusion was begun for Group A and Group B, 0.5 µg kg -1h -1 and 0.25 µg kg -1 h -1 respectively and Goup C were infused serum physiologic. During the operation, hemodynamic parameters, neuromuscular function, BIS and total amount of desflurane were recorded. Results: Total desflurane consumptions (Group A: 50.12±15 ml, Group B: 80.26±13.7 ml, Group C:92.19±25.1 ml), additional dose of fentanyl and the onset time of rocuronium in Group A were statistical difference lower than other groups. Conclusion: It was concluded that administration of dexmedetomidine as a bolus of 1µkg -1 and as an infusion dose of 0.5 µkg -1 h -1 decreases the onset time of rocuronium, and decreases desflurane consumption by 45% in accordance with the control group, and reduces intraoperative requirement for additional analgesic dose.en_US
dc.identifier.endpage118en_US
dc.identifier.issn1300199X
dc.identifier.issn1300-199Xen_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage110en_US
dc.identifier.urihttps://hdl.handle.net/11454/20347
dc.identifier.volume31en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofErciyes Tip Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDesfluraneen_US
dc.subjectDexmedetomidineen_US
dc.subjectNeuromuscular blockadeen_US
dc.titleEffects of two different doses of dexmedetomidine on intraoperative desflurane consumption, hemodynamic parameters and neuromuscular blockade [İki farkli deksmedetomidin dozunun i·ntraoperatif desfluran tüketimi, hemodinamik parametreler ve kas gevşemesi üzerine olan etkileri]en_US
dc.typeArticleen_US

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