Vitamin D and the immune system: Medical education

Küçük Resim Yok

Tarih

2008

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Ortadogu Ad Pres & Publ Co

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Vitamin D plays important role in calcium homeostasis and bone metabolism. However, the researches performed during the past twenty years revealed that it also has a significant immunomodulatory effect. D vitamin deficiency has been shown to be related to increased tendency for development of several autoimmune diseases such as type 1 diabetes and inflammatory bowel diseases. D vitamin deficiency has also been associated with increased risk of development of infections such as tuberculosis and malignancy. In experimental models, it has been found to be successful in reducing the risk of graft rejection. D vitamin has been found to have salutary effects on renal allograft function. The findings of the researches indicate that vitamin D might have a role as an alternative and safer treatment modality in many autoimmune diaseases and transplantation practice.

Açıklama

Anahtar Kelimeler

calcitriol, 24,25-dihydroxycholecalciferol receptor, receptors, calcitriol

Kaynak

Turkiye Klinikleri Tip Bilimleri Dergisi

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

28

Sayı

2

Künye