Standardized method comparison for ACS:180 plus and immulite sensitive PSA (sPSA) measurement methods

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dc.contributor.authorKurtulmus Y.
dc.contributor.authorTanyalçin T.
dc.contributor.authorBozkaya G.
dc.contributor.authorGündüz O.
dc.contributor.authorÇerçi Ö.
dc.contributor.authorKutay F.Z.
dc.contributor.authorErsöz B.
dc.date.accessioned2019-10-27T09:00:13Z
dc.date.available2019-10-27T09:00:13Z
dc.date.issued2001
dc.departmentEge Üniversitesien_US
dc.description.abstractThe aim of this study was to compare two immunoassay measurement methods, the ACS: 180 Plus (Chiron Diagnostics) kit and the Immulite sPSA (DPC) kit. Method comparison analysis was performed according to EP9-A; approved guideline of NCCLS 51. Serum samples having a wide range of total prostate-specific antigen (PSA) concentrations were evaluated in split-sample analysis. F-test, t-est analysis and regression statistics were performed. In Deming regression analysis the coefficients were as follows; the slope=0.967; y-intercept=-0.148, r=0.989. An acceptable bias was seen since the systematical error was calculated to have a value less than the total allowable error calculated from biological variations. Nonparametric evaluation of the area under ROC curves for ACS: 180 Plus and Immulite sPSA were 0.997 and 0.987, respectively. Diagnostic accuracy was at the level of p= 0.000 and no statistical difference was found between the two assay methods.en_US
dc.identifier.doi10.1007/PL00010466
dc.identifier.endpage426en_US
dc.identifier.issn0949-1775
dc.identifier.issn0949-1775en_US
dc.identifier.issue09.Octen_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage424en_US
dc.identifier.urihttps://doi.org/10.1007/PL00010466
dc.identifier.urihttps://hdl.handle.net/11454/28015
dc.identifier.volume6en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer New Yorken_US
dc.relation.ispartofAccreditation and Quality Assuranceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPSAen_US
dc.subjectROC curve analysisen_US
dc.subjectStandardized method comparisonen_US
dc.titleStandardized method comparison for ACS:180 plus and immulite sensitive PSA (sPSA) measurement methodsen_US
dc.typeArticleen_US

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