Evaluation of sexual dysfunction in patients with luts, relationship with testosterone, leptin and serum lipid levels: Re-evaluation after alpha blocker treatment [Alt üri·ner si·stem semptomlu hastalarda ci·nsel di·sfonksi·yonun araştirilmasi, testosteron, lepti·n, kan li·pi·dleri·i·le i·li·şki·si·: Alfa bloker (tamsulo?in) tedavi·si·sonrasi yeni·den degerlen?irme]

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dc.contributor.authorRodoplu A.
dc.contributor.authorTurna B.
dc.contributor.authorAltay B.
dc.contributor.authorUmul M.
dc.contributor.authorSemerci B.
dc.date.accessioned2019-10-27T00:10:08Z
dc.date.available2019-10-27T00:10:08Z
dc.date.issued2005
dc.departmentEge Üniversitesien_US
dc.description.abstractIntroduction: Lower urinary tract symptoms (LUTS) associated with BPH and erectile dysfunction (ED) are common problems in aging male. In this study, we aimed to determine the causes of the relationship between LUTS and ED, and the possible effects of body mass index (BMI), serum leptin, free testosterone (IT) and lipid levels on LUTS and ED etiology. Materials and methods: Between June 2003 and February 2004, 46 patients were recruited in this study. All patients underwent physical examination including digital rectal examination, urine analysis, uroflowmetry and residual urine volume assessment. Serum leptin, lipid and free testosterone levels were analyzed. All patients' BMI were determined. Thirty-three patients received alpha blocker treatment and 13 patients were in the watchful waiting group. Erectile capacity and voiding symptoms of the patients were analyzed with International Index of Erectile Function (IIEF-5), International Prostate Symptom Score (IPSS), respectively before and after alpha blocker treatments. Ejaculatory function was assessed with Danish Prostate Symptom Score sexual-function questionnaire (DAN-PSSsex). Data were analyzed using the Pearson correlation test, Mann-Whitney test and Kruskal-Wallis test. Results: There was a negative correlation between IPSS and IIEF (p<0.05). The incidences of ED in patients with LUTS were 50%, 81.8% and 69.2% in patients with mild, moderate and severe symptom, respectively. The frequency of erectile dysfunction was very high in patients especially with moderate symptoms. After alpha blocker treatment the percentage of patients with mild symptoms decreased, but those with moderate and severe symptoms increased. In our study there was no significant correlation between IIEF and fT levels but the mean level of fT in patients with ED was under 15 ng/ml. There was no correlation between serum lipid levels and the other parameters. Conclusion: There is a strong correlation between LUTS and ED. As the severity of LUTS increases the incidence of ED increases. Alpha blocker treatment seems to slightly increase the incidence of ED and ejaculatory problems. Patients with LUTS and ED have lower levels of fT, but this is not statistically significant. There is no correlation between serum lipids and other parameters. Leptin levels might be important in predicting LUTS and ED relationship for future research.en_US
dc.identifier.endpage515en_US
dc.identifier.issn1300-5804
dc.identifier.issn1300-5804en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage508en_US
dc.identifier.urihttps://hdl.handle.net/11454/21884
dc.identifier.volume31en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Uroloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectErectile dysfunctionen_US
dc.subjectLeptinen_US
dc.subjectLower urinary tract symptomsen_US
dc.subjectTestosteroneen_US
dc.titleEvaluation of sexual dysfunction in patients with luts, relationship with testosterone, leptin and serum lipid levels: Re-evaluation after alpha blocker treatment [Alt üri·ner si·stem semptomlu hastalarda ci·nsel di·sfonksi·yonun araştirilmasi, testosteron, lepti·n, kan li·pi·dleri·i·le i·li·şki·si·: Alfa bloker (tamsulo?in) tedavi·si·sonrasi yeni·den degerlen?irme]en_US
dc.typeArticleen_US

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