Changes in liver and kidney antioxidant enzyme activities in the rainbow trout (Oncorhynchusmykiss) exposed cadmium

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dc.contributor.authorHisar O.
dc.contributor.authorYildirim S.
dc.contributor.authorSönmez A.Y.
dc.contributor.authorAras H.N.
dc.contributor.authorGultepe N.
dc.date.accessioned2019-10-26T23:00:34Z
dc.date.available2019-10-26T23:00:34Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description.abstractIn vivo effects of cadmium on antioxidant enzymes such as super- oxide dismutase (SOD), catalase (CAT), glutathione Peroxidase (GPx) and glutathione reductase (GSR) investigated in liver and kidney tissues of rainbow trout (Oncorhynchus mykiss). Three test groups of fish were subjected to cadmium in concentrations of 0 (control), 1 and 5 ppm. The duration of exposure was 1,3,5 and 7 d. The antioxidant enzyme activities, measured liver and kidney homogenates, were stimulated by both concentration (1 and 5 ppm) of cadmium chloride. Moreover, the dose-response patterns of the antioxidant enzyme activities in the liver and kidney tissue were very similar. All antioxidant enzyme activities were significantly stimulated on the first day of experiment (Day 1) in the tissues at the both dose of Cd (p < 0.05) while CAT activity was stimulated after 3 days in the tissues at a dose of 1 ppm Cd (p < 0.05). The stimulation effect of Cd on SOD, GPx and GSR activities in the tissues diminished after 7 d cadmium administration. However, this effect of Cd on CAT activity diminished after 5 d. These findings indicate that the tissue antioxidant enzymes function to protect against cadmium toxicity.en_US
dc.identifier.endpage3137en_US
dc.identifier.issn0970-7077
dc.identifier.issn0970-7077en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage3133en_US
dc.identifier.urihttps://hdl.handle.net/11454/20560
dc.identifier.volume21en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofAsian Journal of Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidant enzymesen_US
dc.subjectCadmiumen_US
dc.subjectRainbow trouten_US
dc.titleChanges in liver and kidney antioxidant enzyme activities in the rainbow trout (Oncorhynchusmykiss) exposed cadmiumen_US
dc.typeArticleen_US

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