Application of Centri-voltammetry to Cytosensors: Cyto-centrivoltammetry
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Pergamon-Elsevier Science Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this work, a centri-voltammetric cytosensor suitable for the for detection of folate receptor positive cervical cancer (HeLa) cells was developed for the first time. In order to see the effect of centrifugation, developed cytosensor's performance was compared in terms of analytical characteristics values, in the presence and absence of centri-voltammetry. As a result, in the absence of centri-voltammetry, the linear range was found between 75 cells/mL and 10(6) cells/mL with limit of detection (LOD) value as 75 cells/mL and with R.S.D value of 3.5% (for 5.0 x 10(4) HeLa cells/mL (n = 3)). Meanwhile in the presence of centri-voltammetry, the linear range was found between 8.0 cells/mL and 5 x 10(6) cells/mL and LOD value was calculated as 8 cells/mL with R.S.D value of 4.7% for the same concentration. (C) 2016 Elsevier Ltd. All rights reserved.
Açıklama
Anahtar Kelimeler
Centri-voltammetry, HeLa cells, PAMAM, Electrochemical cytosensor
Kaynak
Electrochimica Acta
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
211