Osmotic release oral system methylphenidate is more effective than immediate release methylphenidate: A retrospective chart review in turkish children with attention deficit hyperactivity disorder [OROS-metilfenidat ir-metilfenidattan daha etkilidir: Dikkat eksikliği hiperaktivite bozukluğu olan türk çocuklarında retrospektif bir araştırma]
Küçük Resim Yok
Tarih
2014
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Cukurova Univ Tip Fakultesi Psikiyatri Anabilim Dali
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: The aim of this study was to evaluate the efficacy and safety of osmotic release oral system methylphenidate (OROS-MPH) compared with immediate release methylphenidate (IR-MPH) in Turkish children with attention deficit hyperactivity disorder (ADHD).Method: The medical records of primary school-aged children, who were first-time referrals to the outpatient clinic, were reviewed; 67 children receiving OROS-MPH and 47 children receiving IR-MPH were recruited for the study. A total of 114 children receiving treatment for ADHD were evaluated over 8 weeks.Results: The total Turgay DSM-IV Based Child and Adolescent Behavior Disorders Screening and Rating Scale scores from both the parent and teacher forms decreased significantly in both groups over 8 weeks (p<0.001). OROS-MPH was found to be superior to IR-MPH when comparing baseline-to-8th-week- mean inattention score changes on both the teacher (p=0.007) and parent (p=0.015) forms. OROS-MPH and IR-MPH were both well tolerated, with similar side- effect profiles.Conclusion: OROS-MPH was found to be effective and safe in the treatment of ADHD symptoms in Turkish children. © 2014, Cukurova Univ Tip Fakultesi Psikiyatri Anabilim Dali. All rights reserved.
Açıklama
Anahtar Kelimeler
Attention deficit hyperactivity disorder, Children, Methylphenidate
Kaynak
Klinik Psikofarmakoloji Bulteni
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
24
Sayı
4
