Gastro-esophageal reflux following Helicobacter pylori eradication [Helicobacter pylori eradikasyonundan sonra gastroozofajial reflu sendromu]

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dc.contributor.authorGunsar F.
dc.contributor.authorAydin A.
dc.contributor.authorErsoz G.
dc.contributor.authorYilmaz M.
dc.contributor.authorAkarca U.S.
dc.contributor.authorOzutemiz O.
dc.contributor.authorAlkanat M.
dc.contributor.authorCavusoglu H.
dc.date.accessioned2019-10-27T00:26:30Z
dc.date.available2019-10-27T00:26:30Z
dc.date.issued1999
dc.departmentEge Üniversitesien_US
dc.description.abstractThe interrelation between Helicobacter pylori (H. pylori) and gastro- esophageal reflux disease is complex and not fully understood. It has recently been reported that eradication of H. pylori infection in patients with duodenal ulcer may provoke reflux esophagitis. In order to determine whether H. pylori eradication promotes the development of gastro-esophageal reflux and reflux oesophagitis, we performed endoscopy, esophageal manometry and 24-hour intraesophageal pH-monitoring prior to and following H. pylori eradication. Biopsies were taken from the antrum, corpus and esophagus during endoscopy. Whilst the study group comprised 21 patients, results were evaluated in only 19 (10 duodenal ulcer and nine non-ulcer dyspepsia) in whom H. pylori eradication was achieved. After eradication all parameters of pH monitoring were increased (p < 0.05) and these the changes were more pronounced in patients with corpus gastritis or esophagitis (p < 0.05). Esophagitis increased from 21% to 47% endoscopically and from 73% to 84% endoscopically and histologically following eradication but this increase was not significant. In conclusion, H. pylori eradication caused an increase in gastro-oesophageal refux, especially in patients with corpus gastritis or esophagitis.en_US
dc.identifier.endpage418en_US
dc.identifier.issn1300-4948
dc.identifier.issn1300-4948en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage411en_US
dc.identifier.urihttps://hdl.handle.net/11454/23402
dc.identifier.volume10en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGastro-oesophageal reflux syndromeen_US
dc.subjectHelicobacter pylorien_US
dc.titleGastro-esophageal reflux following Helicobacter pylori eradication [Helicobacter pylori eradikasyonundan sonra gastroozofajial reflu sendromu]en_US
dc.typeArticleen_US

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