Development of beta-TCP Block Grafts with Tunable Porosity and Mechanical Properties

In the scope of bone tissue engineering, there has still been great amount of demand on synthetic bone graft that induces differentiation of osteoprogenitor cells by cell matrix interaction at the nanoscale as well as mimicking micro assembly of compact bone while providing high mechanical strength. In this study, we aimed to develop synthetic bone grafts based on beta-tricalcium phosphate (beta-TCP) in the form of rod, block and cylinder with tunable porosity, radiopaque and mechanical properties.