Comparison of serological and clinical findings in Turkish patients with cystic echinococcosis

dc.contributor.authorYolasigmaz, A.
dc.contributor.authorReiterova, K.
dc.contributor.authorTurk, M.
dc.contributor.authorReyhan, E.
dc.contributor.authorBozdag, A. D.
dc.contributor.authorKarababa, A. O.
dc.contributor.authorAltintas, Nuray
dc.contributor.authorAltintas, Nasmiye
dc.date.accessioned2019-10-27T19:40:03Z
dc.date.available2019-10-27T19:40:03Z
dc.date.issued2006
dc.departmentEge Üniversitesien_US
dc.description.abstractCystic echinococcosis (CE), caused by the cestode Echinococcus granulosus, is potentially dangerous for humans. The aim of this study was to examine serological and clinical findings regarding cysts localisation and individual responses in 54 patients with CE. The majority of patients in this study were females (63%) and the average age was 46.3 years. Most of the patients lived in rural areas or kept a dog (46%) for a long time. The most frequent symptoms were hypochondrial pain (48.9%), epigastrial discomfort (27.7%), vomiting (21.3%), minor cough (12.8%), urticaria (6.3%), weakness (4.3%), fever (2.1%), side- or backache (4.3%). However, 17% of the patients showed no symptoms. In every case, the ultrasound (USG) and/or computer tomography (CT) investigations were positive. In most cases (53.2% of the patients) a single cyst was found but 46.8% of the patients had multiple cyst formations (from 2 to 9 cysts) located in the liver. Sporadic lung, splenetic, mesenterial, tibial and cerebral localisations were also found. The patients were individually treated with albendazol (10 - 15 mg/kg) five days prior and six months after the surgical treatment. Serum samples were investigated by the serological techniques: IHAT, ELISA and Western blot using hydatid fluid antigen. In the patient sera, the specific antibody levels were mostly increased after surgery. Different results were obtained only in two patients. In the first case, seroconversion was delayed. In the other case all ELISA results were negative, however, the Western blot analysis and surgery proved the presence of CE. The results suggest that the different antibody response of patients depends on the individual immune response. Multiple localization and various stages of CE cysts demonstrate the necessity of a complex approach for the confirmation of a correct diagnosis.en_US
dc.identifier.doi10.2478/s11687-006-0041-x
dc.identifier.endpage225en_US
dc.identifier.issn0440-6605
dc.identifier.issn1336-9083
dc.identifier.issn0440-6605en_US
dc.identifier.issn1336-9083en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage220en_US
dc.identifier.urihttps://doi.org/10.2478/s11687-006-0041-x
dc.identifier.urihttps://hdl.handle.net/11454/40223
dc.identifier.volume43en_US
dc.identifier.wosWOS:000243263400006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofHelminthologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEchinococcus granulosusen_US
dc.subjectcystic echinococcosisen_US
dc.subjectclinical findingen_US
dc.subjectserodiagnosisen_US
dc.subjectTurkeyen_US
dc.titleComparison of serological and clinical findings in Turkish patients with cystic echinococcosisen_US
dc.typeArticleen_US

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