Transcatheter Ductus Arteriosus Closure with Various Devices in the Pediatric Patient Group and Long-term Outcomes: Experience from a Single Center

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dc.authorid0000-0002-1352-7958
dc.authorid0000-0002-0340-7741
dc.authorid0000-0002-5951-5928
dc.authorid0000-0003-1828-1501
dc.authorid0000-0002-7878-7531
dc.authorid0000-0001-8054-4806
dc.authorid0000-0003-4708-0442
dc.contributor.authorOn, Seyma Sebnem
dc.contributor.authorDogan, Eser
dc.contributor.authorErgin, Firat
dc.contributor.authorBeyter, Mehmet Baki
dc.contributor.authorKafikci, Gulcin Kayan
dc.contributor.authorYilmaz, Meral
dc.contributor.authorLevent, Refit Erturk
dc.contributor.authorAcar, Burcu Bufra
dc.contributor.authorBeci, Burcugul Karasulu
dc.contributor.authorTutar, Zulal Ulger
dc.date.accessioned2025-03-11T11:12:35Z
dc.date.available2025-03-11T11:12:35Z
dc.date.issued2024
dc.departmentEge Üniversitesi, Tıp Fakültesi, Dahili Bilimler Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractAim: The emergence of advanced duct occluder devices has made transcatheter patent ductus arteriosus (PDA) closure the preferred treatment for pediatric patients. This study compared the effectiveness, safety, and long-term outcomes of various transcatheter PDA closure devices. Materials and Methods: This study involved 320 patients aged 0 to 18 years who underwent transcatheter PDA closure at our hospital from 2004 to 2023. We retrospectively reviewed their records in order to assess procedure success, demographic information, clinical features, angiographic parameters, and complications. Patients were categorized by closure type: Group I for coil closure, Group II for Amplatzer Duct Occluder (ADO)-I closure, and Group III for ADO-II closure. Results: In this study of 320 patients, 203 (63.4%) were female and 117 (36.4%) male. The average age was 56.5 months (+/- 49.6), with a median weight of 15 kg (interquartile range 10.5-23 kg). The median diameter of the PDA at its narrowest point was 2.0 mm (interquartile range 2-3 mm). Ductal anatomy distribution was as follows: Type A (176 patients, 55%), type B (49 patients, 15.3%), type C (30 patients, 9.3%), type D (5 patients, 1.56%), type E (57 patients, 17.8%), and type F (4 patients, 1.25%). Arterial access was used in 263 patients (82.1%), and venous plus arterial access in 57 patients (17.8%). Closure techniques included the ADO-II in 107 cases (33.4%), ADO-I in 12 cases (3.75%), and coils in 201 cases (62%). The early closure rate was 97.5%, with initial shunt rates of 0.6% and 0.3% at one month. Device embolization occurred in 5 patients (1.87%). By the six-month follow-up, all PDAs had closed, resulting in an overall transaction success rate of 97.5%. The average followup period was 105.8 +/- 55 months. Conclusion: Percutaneous closure of PDA in children is safe and effective, with a high success rate. Key factors include the patient's age, weight, duct dimensions, and the type and size of the PDA. ADO-I devices are ideal for larger defects, while coil or ADO-II devices are preferable for smaller ones. Proper patient selection is critical for successful outcomes.
dc.identifier.citationÖn, Ş. Ş., Doğan, E., Ergin, F., Beyter, M. B., Kayan Kaşıkçı, G., Yılmaz, M., Acar, B. B., Karasulu Beci, B., Ülger Tutar, Z., & Levent, R. E. (2024). Transcatheter ductus arteriosus closure with various devices in the pediatric patient group and long-term outcomes: Experience from a single center. The Journal of Pediatric Research, 11(4), 207-211.
dc.identifier.doi10.4274/jpr.galenos.2024.69094
dc.identifier.endpage211
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85212137763
dc.identifier.scopusqualityQ4
dc.identifier.startpage207
dc.identifier.urihttps://doi.org/10.4274/jpr.galenos.2024.69094
dc.identifier.uri2147-9445
dc.identifier.urihttps://hdl.handle.net/11454/116611
dc.identifier.volume11
dc.identifier.wosWOS:001377176800001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorOn, Seyma Sebnem
dc.institutionauthorDogan, Eser
dc.institutionauthorErgin, Firat
dc.institutionauthorBeyter, Mehmet Baki
dc.institutionauthorKafikci, Gulcin Kayan
dc.institutionauthorYilmaz, Meral
dc.institutionauthorLevent, Refit Erturk
dc.institutionauthorAcar, Burcu Bufra
dc.institutionauthorBeci, Burcugul Karasulu
dc.institutionauthorTutar, Zulal Ulger
dc.institutionauthorid0000-0002-1352-7958
dc.institutionauthorid0000-0002-0340-7741
dc.institutionauthorid0000-0002-5951-5928
dc.institutionauthorid0000-0003-1828-1501
dc.institutionauthorid0000-0002-7878-7531
dc.institutionauthorid0000-0001-8054-4806
dc.institutionauthorid0000-0003-4708-0442
dc.language.isoen
dc.publisherGalenos Publishing House
dc.relation.ispartofThe Journal of Pediatric Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectChildren
dc.subjectpatent ductus arteriosus
dc.subjectPDA closure devices
dc.subjectpercutaneous PDA closure
dc.titleTranscatheter Ductus Arteriosus Closure with Various Devices in the Pediatric Patient Group and Long-term Outcomes: Experience from a Single Center
dc.typeArticle

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