Study of Radiotherapy Properties and Antimicrobial Activity of Glyconanoparticles (GNPs) Generated from Imidazolium Salts

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dc.authoridYavuz, Murat/0000-0003-3452-8551
dc.authoridTelli, Fatma Cetin/0000-0003-2302-6409
dc.authorscopusid55357299600
dc.authorscopusid23037730000
dc.authorscopusid16038428400
dc.authorscopusid6507939084
dc.authorwosidYavuz, Murat/D-1679-2013
dc.contributor.authorTelli, Fatma Cetin
dc.contributor.authorYavuz, Murat
dc.contributor.authorDenizalti, Serpil
dc.contributor.authorSalman, Yesim
dc.date.accessioned2024-08-25T18:51:20Z
dc.date.available2024-08-25T18:51:20Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractCarbohydrate-based imidazolium salts (IMSs) are structural patterns for the synthesis of pharmaceutically and biologically active substances. For this purpose, the chiral furanoside-based imidazolium salt conjugated with a cysteamine (Cyt) linker attached gold and silver nanoparticles were prepared in this study. The biological applications of the HeLa and A549 cell lines using MTT cell proliferation method were exhibited to determine the biological evaluation of NPs conjugated with sugar based imidazolium salt. The satisfactory results obtained demonstrated that the synthesized glyconanoconjugates were radiotherapeutic agents. Moreover, this modification type within a galactose derived imidazolium salt is the first work in bioapplications, especially in radiotherapy. The antimicrobial activity of IMSs and their nanoconjugates against test pathogens was also evaluated using the disc diffusion technique.en_US
dc.description.sponsorshipEge University [FGA-2019-20195]en_US
dc.description.sponsorshipWe would like to Ege University for financial support of this work (FGA-2019-20195). The authors would like to thank Dicle University Science and Technology Research and Application Center (DUBTAM) for TEM, SEM and SEM/EDX characterizations. We also thank the Ege University Central Research Testing and Analysis Laboratory Research and Application Center (EGE-MATAL) for cell culture test analysis.en_US
dc.identifier.doi10.1002/slct.202203810
dc.identifier.issn2365-6549
dc.identifier.issue13en_US
dc.identifier.scopus2-s2.0-85152057129en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1002/slct.202203810
dc.identifier.urihttps://hdl.handle.net/11454/102543
dc.identifier.volume8en_US
dc.identifier.wosWOS:000965082800011 - WOS:000962846900001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofChemistryselecten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240825_Gen_US
dc.subjectAntimicrobial activityen_US
dc.subjectGlyconanoconjugatesen_US
dc.subjectGlyconanoparticlesen_US
dc.subjectImidazolium saltsen_US
dc.subjectRadiosensitivityen_US
dc.subjectSchiff-Base Ligandsen_US
dc.subjectSilver Nanoparticlesen_US
dc.subjectHeterocyclic Carbenesen_US
dc.subjectGold Nanoparticlesen_US
dc.subjectComplexesen_US
dc.subjectDissolutionen_US
dc.subjectReductionen_US
dc.subjectDeliveryen_US
dc.subjectOxideen_US
dc.titleStudy of Radiotherapy Properties and Antimicrobial Activity of Glyconanoparticles (GNPs) Generated from Imidazolium Saltsen_US
dc.typeArticleen_US

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