Complications of Varicella in Healthy Children: Is It Increasing?

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dc.contributor.authorKoturoglu, Guldane
dc.contributor.authorKurugol, Zafer
dc.contributor.authorHalicioglu, Oya
dc.contributor.authorDevrim, Ilker
dc.contributor.authorVardar, Fadil
dc.date.accessioned2019-10-27T20:25:11Z
dc.date.available2019-10-27T20:25:11Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: Varicella is a common and self-limiting disease caused by the varicella zoster. However it may cause severe morbidity and mortality, due to complications in healthy children. These complications can be prevented by vaccination. The aim of this study was to determine the type of complications of varicella in hospitalized children. Also these data were compared with the study carried out in 2005 and changes in the varicella hospitalizations were analyzed to obtain the necessary data for the study of the vaccine. Materials and Methods: A retrospective study involving 262 children hospitalized for complications due to varicella between January 2005 and December 2009 was carried out. Incidence and clinical spectrum of complications and their age and seasonal variations related distribution was analyzed. Results: We identified 262 children hospitalized for complications of varicella. Fourteen children with immune deficiency or on immunosuppressive treatment were excluded. The majority of varicella complications occurred in children under 5 years of age. The most common complications were infectious complications (41.9%). Thereafter, neurologic complications (35.6%) and hematological complications were seen (3.6%). The seasonal distribution of complications associated with varicella had a higher incidence in January (21.4%). Three patients died due to these complications. Conclusion: Complications of varicella were more frequent than previously reported. Also mortality rates were higher than those in the previous study. Varicella can be accompanied by severe complications and death in immunologically healthy children. In this study, the importance of varicella vaccination was emphasized again.en_US
dc.identifier.doi10.4274/jpr.95967
dc.identifier.endpage77en_US
dc.identifier.issn2147-9445
dc.identifier.issue2en_US
dc.identifier.startpage74en_US
dc.identifier.urihttps://doi.org/10.4274/jpr.95967
dc.identifier.urihttps://hdl.handle.net/11454/42206
dc.identifier.volume2en_US
dc.identifier.wosWOS:000219056100005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofJournal of Pediatric Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectVaricellaen_US
dc.subjectcomplicationsen_US
dc.subjectchildrenen_US
dc.titleComplications of Varicella in Healthy Children: Is It Increasing?en_US
dc.typeArticleen_US

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