Novel Benzimidazole- Platinum(II) Complexes: Synthesis, Characterization, Antimicrobial and Anticancer Activity

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dc.contributor.authorDogan, Umut
dc.contributor.authorOzcan, Ozge
dc.contributor.authorAlaca, Gizem
dc.contributor.authorAri, Aydan
dc.contributor.authorGunnaz, Salih
dc.contributor.authorYalcin, H. Tansel
dc.contributor.authorIrisli, Sevil
dc.date.accessioned2021-05-03T20:21:28Z
dc.date.available2021-05-03T20:21:28Z
dc.date.issued2021
dc.departmentEge Üniversitesien_US
dc.description.abstractThree new Platinum complexes (1-3) with 2,6-di-tert-butyl-4-(1-phenyl-1H-benzimidazol-2-yl) phenol (L-1), N, N-dimethyl-4-(1-phenyl-1H-benzimidazol-2-yl) aniline (L-2) and 4-(1H-benzimidazol-2-yl)-N, N-dimethylaniline (L-3) were prepared and characterized by FT-IR, NMR and Elemental analyses. The crystal structures of L-1, 1 and geometrical isomer of 1 (1a) were determined by X-Ray crystallography. The cytotoxic activities of the compounds were tested on against SHSY-5Y and U-87 cell lines. The antimicrobial evaluations of the compounds showed that they have a moderate antimicrobial effect on gram positive and gram negative bacteria. (C) 2020 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.molstruc.2020.129785
dc.identifier.issn0022-2860
dc.identifier.issn1872-8014
dc.identifier.issn0022-2860en_US
dc.identifier.issn1872-8014en_US
dc.identifier.scopus2-s2.0-85098978514en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.molstruc.2020.129785
dc.identifier.urihttps://hdl.handle.net/11454/69334
dc.identifier.volume1229en_US
dc.identifier.wosWOS:000619137200001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofJournal of Molecular Structureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBenzimidazoleen_US
dc.subjectBenzimidazole platinum (II) complexesen_US
dc.subjectCytotoxicityen_US
dc.subjectAntimicrobial activityen_US
dc.titleNovel Benzimidazole- Platinum(II) Complexes: Synthesis, Characterization, Antimicrobial and Anticancer Activityen_US
dc.typeArticleen_US

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