The effect of dehydrobenzperidol on nausea and vomiting in patient controlled analgesia [Hasta kontrollu analjezide dehydrobenzperidol postoperatif bulanti ve kusmaya etkisi]
| dc.contributor.author | Ongun B. | |
| dc.contributor.author | Agrali S. | |
| dc.contributor.author | Sakarya M. | |
| dc.contributor.author | Gokpinar B. | |
| dc.contributor.author | Ugur G. | |
| dc.date.accessioned | 2019-10-27T00:26:01Z | |
| dc.date.available | 2019-10-27T00:26:01Z | |
| dc.date.issued | 2000 | |
| dc.department | Ege Üniversitesi | en_US |
| dc.description.abstract | This study aims to reveal the efficacy of droperidol, a neuroleptic drug with anti-emetic properties, in preventing postoperative nausea and vomiting (PONV) due to IV morphine administered during patient controlled analgesia (PCA). Thirty patients of ASA I-II to whom abdominal hysterectomy was applied were randomly allocated into two groups to receive PCA by morphine alone (Group I) or in combination with dehydrobenzperidol (DHBP) (Group II). Group I received a loading dose of 5 mg IV morphine followed by 1 mg IV boluses with a 10 min lockout period while Group II received morphine plus dehydrobenzperidol (0.05 mg/mL) infusion following loading dose. Otherwise the protocol were the same. Pain and sedation scores, mean and cumulative morphine requirements, incidence of side effects, and vital functions were recorded hourly for 24 hours. Morphine requirement did not show difference between groups. Initial and first hour VAS value was higher in Group I. PONV incidence was significantly lower in Group II (p<0.05), 6.7% vs. 28.6%. None of the patients showed side effects such as respiratory depression, significant haemodynamic changes, and extrapyramidal effects. It is concluded that the addition of DHBP to morphine in intravenous PCA lowered the incidence of PONV safely. | en_US |
| dc.identifier.endpage | 16 | en_US |
| dc.identifier.issn | 1016-5150 | |
| dc.identifier.issn | 1016-5150 | en_US |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.scopusquality | N/A | en_US |
| dc.identifier.startpage | 11 | en_US |
| dc.identifier.uri | https://hdl.handle.net/11454/23338 | |
| dc.identifier.volume | 28 | en_US |
| dc.indekslendigikaynak | Scopus | en_US |
| dc.language.iso | tr | en_US |
| dc.relation.ispartof | Turk Anesteziyoloji ve Reanimasyon | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | DHBP | en_US |
| dc.subject | Morphine | en_US |
| dc.subject | Nausea | en_US |
| dc.subject | Patient controlled analgesia | en_US |
| dc.subject | Vomiting | en_US |
| dc.title | The effect of dehydrobenzperidol on nausea and vomiting in patient controlled analgesia [Hasta kontrollu analjezide dehydrobenzperidol postoperatif bulanti ve kusmaya etkisi] | en_US |
| dc.type | Article | en_US |
