Allogenic stem cell transplantation and total body irradiation

dc.contributor.authorKamer S.
dc.date.accessioned2019-10-27T08:20:43Z
dc.date.available2019-10-27T08:20:43Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractThe clinical importance of bone marrow transplantation has increased considerably in recent decades. More than 450 centers for bone marrow transplantation now exist worldwide, performing more than 5000 transplantations per year. The number of transplant centers and patients has increased dramatically in Turkey in the last several years. When transplant donor and recipient are different individuals, hematopoietic graft is known as allogeneic graft. Total body irradiation (TBI) remains an important component of allogeneic hematopoietic stem cell transplant, with the goal of eradicating residual malignant cells and modulating the immune system of the transplant recipient. TBI is especially advantageous in allogeneic stem cell transplantation, since its biological effects can be exerted uniformly without sparing the “sanctuary” sites, such as nervous system or testicles. In this report, the role of TBI in allogeneic stem cell transplantation is reviewed. © 2016, Turkish Society for Radiation Oncology.en_US
dc.identifier.doi10.5505/tjo.2016.1499
dc.identifier.endpage116en_US
dc.identifier.issn1300-7467
dc.identifier.issn1300-7467en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage113en_US
dc.identifier.urihttps://doi.org/10.5505/tjo.2016.1499
dc.identifier.urihttps://hdl.handle.net/11454/25776
dc.identifier.volume31en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherIstanbul Tip Fakultesien_US
dc.relation.ispartofTurk Onkoloji Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAllogenic stem cell transplantationen_US
dc.subjectBone marrow donoren_US
dc.subjectTotal body irradiationen_US
dc.titleAllogenic stem cell transplantation and total body irradiationen_US
dc.typeReview Articleen_US

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