The Present and Future Aspects of Life-Long Pertussis Prevention: Narrative Review with Regional Perspectives for Türkiye

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dc.authorscopusid57216386080
dc.authorscopusid6602301979
dc.authorscopusid7102824838
dc.authorscopusid7003673004
dc.authorscopusid12794749100
dc.authorscopusid19639799200
dc.authorscopusid6507394002
dc.contributor.authorPehlivan, T.
dc.contributor.authorDinleyici, E.C.
dc.contributor.authorKara, A.
dc.contributor.authorKurugöl, Z.
dc.contributor.authorTezer, H.
dc.contributor.authorAksakal, N.B.
dc.contributor.authorBiri, A.
dc.date.accessioned2024-08-25T18:51:02Z
dc.date.available2024-08-25T18:51:02Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractPertussis, caused by Bordetella pertussis, remains one of the most widespread, contagious, and vaccine-preventable diseases. It results in notable morbidity and mortality as well as severe medical, social, and economic burden. Despite high global vaccine coverage, pertussis continues to be a significant epidemiologic problem, with outbreak episodes every few years just as in the pre-vaccination era. In Türkiye, there is a lack of comprehensive data on the current burden of pertussis in different age and risk groups, leading to underdiagnosis and underreporting of the disease, especially in adults who are often not considered at risk. Available data from Türkiye also reveal inadequate levels of protective antibodies in preterm newborns, emphasizing the need for additional preventive measures. Authors stated that improving physician awareness of pertussis symptoms in patients with prolonged cough, increasing access to routine pertussis tests, and conducting surveillance studies would aid in accurate diagnosis and reporting in Türkiye. As the Turkish Ministry of Health Antenatal Care Management Guide suggests routine second and third pregnancy check-up visits at weeks 18–24 and 28–32 correspondingly, this period can be considered the ideal vaccination time for Türkiye. Introducing a booster dose of Tdap at around 10 years of age or during national military service would reduce transmission and protect susceptible individuals. Identifying individuals at high risk of severe pertussis and prioritizing them for a booster dose is also crucial in Türkiye. Enhancing surveillance systems, increasing healthcare professionals’ awareness through training, and organizing catch-up visits for missed vaccinations during the COVID-19 pandemic are mentioned as additional strategies to improve pertussis prevention in Türkiye. This review focuses on the global and regional burden of pertussis and obstacles to effective prevention and evaluates existing strategies to achieve lifelong pertussis prevention. Literature and current strategies were also discussed from a Turkish national standpoint. © 2023, The Author(s).en_US
dc.description.sponsorshipSanofien_US
dc.description.sponsorshipAuthors’ coordination, editorial assistance, and journal submission assistance were provided by Dr. Ferda Kiziltas at Remedium Consulting Group and funded by Sanofi.en_US
dc.identifier.doi10.1007/s40121-023-00876-0
dc.identifier.issn2193-8229
dc.identifier.scopus2-s2.0-85173720668en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1007/s40121-023-00876-0
dc.identifier.urihttps://hdl.handle.net/11454/102445
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAdisen_US
dc.relation.ispartofInfectious Diseases and Therapyen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240825_Gen_US
dc.subjectBurdenen_US
dc.subjectEpidemiologyen_US
dc.subjectLife-long preventionen_US
dc.subjectPertussisen_US
dc.subjectVaccinationen_US
dc.titleThe Present and Future Aspects of Life-Long Pertussis Prevention: Narrative Review with Regional Perspectives for Türkiyeen_US
dc.typeReview Articleen_US

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