Green Synthesis of Silver Nanoparticles by Using Anthemis Tricolor Boiss., Factorial Design for Parameter Optimization, Characterization and In-Vitro Biological Activities

Basit Öğe Kaydı
dc.authoridFAFAL, TUGCE/0000-0002-7445-5855
dc.contributor.authorTuzun, Burcu Sumer
dc.contributor.authorFafal, Tugce
dc.contributor.authorOzguney, Isik
dc.contributor.authorKivcak, Bijen
dc.date.accessioned2024-08-31T07:47:04Z
dc.date.available2024-08-31T07:47:04Z
dc.date.issued2024
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose The objectives of the study are to obtain silver nanoparticles using Anthemis tricolor in an environmentally friendly, economical, and more effective way with green synthesis and also to determine the most appropriate parameters by examining the effects of preparation conditions on particle size, polydispersity index, and zeta potential using factorial design and further to compare the bioactivity results between water extract and silver nanoparticles. Thus, it is aimed to shed light on further studies on the lightening effects of nanoparticles on the skin. Methods In this study, silver nanoparticles were synthesized by reduction using Anthemis tricolor water extract and silver nitrate solution. Then, various characterization methods (Ultraviolet-Visible Spectroscopy, X-Ray Diffraction analysis) were studied. In addition, the effects of incubation temperature, silver nitrate solution concentration, and extract volume on particle size, zeta potential, and polydispersity index were investigated, and optimum parameters were determined. In addition, antioxidant activities of water extract and silver nanoparticles (DPPH Radical Scavenging Activity, ABTS Radical Cation Scavenging Activity, and Cupric Reducing Antioxidant Capacity) and tyrosinase inhibitory activities were determined. Results According to the results, it was observed that biosynthesis took place with the absorption peak at 440 nm. In addition, changes in peak intensities and shifts in values that occur at the end of nanoparticle formation were determined by Fourier Transform Infrared Spectroscopy. Cubic morphology was determined by Scanning Electron Microscopy. The existence of (111), (200), (220) and (311) planes was proved by X-ray diffraction analysis, confirming the existence of silver nanoparticles in a cubic structure. The optimized parameters were determined for silver nanoparticles obtained by incubating 5 ml of an extract with 1 mM silver nitrate solution at 25 degrees C. Polydispersity index, zeta potential, and particle size values were in the appropriate range. On the other hand, it was observed than silver nanoparticles' antioxidant and tyrosinase inhibitory activities were higher than those the water extract. Conclusion It was concluded that Anthemis tricolor could be presented as an effective, stable, reducing agent. It also suggested that it can be used due to its antioxidant and tyrosinase inhibitory activities and directed to further studies for skin-lightening preparations.en_US
dc.description.sponsorshipEge University BAP [23247]en_US
dc.description.sponsorshipWe would like to thank Ege University BAP project number 23247 for financially supporting the research.en_US
dc.identifier.doi10.1007/s12247-024-09842-w
dc.identifier.issn1872-5120
dc.identifier.issn1939-8042
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85193984231en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1007/s12247-024-09842-w
dc.identifier.urihttps://hdl.handle.net/11454/104304
dc.identifier.volume19en_US
dc.identifier.wosWOS:001228882300001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Pharmaceutical Innovationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240831_Uen_US
dc.subjectAntioxidant Activityen_US
dc.subjectFactorial Designen_US
dc.subjectGreen Synthesisen_US
dc.subjectSilver Nanoparticleen_US
dc.subjectTyrosinase Inhibitor Activityen_US
dc.titleGreen Synthesis of Silver Nanoparticles by Using Anthemis Tricolor Boiss., Factorial Design for Parameter Optimization, Characterization and In-Vitro Biological Activitiesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu