Microbial transformation of Astragalus sapogenins using Cunninghamella blakesleeana NRRL 1369 and Glomerella fusarioides ATCC 9552
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Science Bv
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The microbial transformation of Astragalus sp. derived sapogenins, namely cycloastragenol, astragenol and cyclocanthogenol, by Cunninghamella blakesleeana NRRL 1369 and Glomerella fusarioides ATCC 9552 were investigated. The unique enzyme system of both fungi resulted hydroxylation, cyclization, dehydrogenation and oxidation reactions. Structures of the new metabolites were elucidated by 1-D (H-1, C-13, NOESY), 2-D NMR (DQF-COSY, HMBC, HMQC, NOESY) and HR-MS analyses. (C) 2015 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Astragalus, Microbial transformation, Cycloastragenol, Cyclocanthogenol, Astragenol
Kaynak
Journal of Molecular Catalysis B-Enzymatic
WoS Q Değeri
Q3
Scopus Q Değeri
N/A
Cilt
115
