Evaluation of Vascular Involvement in Children with Celiac Disease

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dc.authoridDoğan, Eser/0000-0002-0340-7741
dc.authoridLevent, Erturk/0000-0002-7878-7531
dc.authoridkiran tasci, ezgi/0000-0001-5842-0292
dc.contributor.authorTasci, Ezgi Kiran
dc.contributor.authorTaner, Sevgin
dc.contributor.authorDogan, Eser
dc.contributor.authorKarakoyun, Miray
dc.contributor.authorBulut, Ipek Kaplan
dc.contributor.authorKabasakal, Caner
dc.contributor.authorLevent, Erturk
dc.date.accessioned2024-08-31T07:46:54Z
dc.date.available2024-08-31T07:46:54Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: Celiac disease is associated with an increased risk of cardiovascular disease due to inflammation and autoimmunity involved in its pathophysiology. We aimed to evaluate vascular involvement in children with celiac disease based on their augmentation index, carotid pulse wave velocity, carotid intima-media thickness, echocardiographic findings, and blood pressure. Materials and Methods:This cross-sectional and controlled study was performed at a single center between 2018 and 2019. The study population consisted of 44 patients with celiac disease who had been on a gluten-free diet for at least one year. Results: We compared celiac patients with a healthy group. While the celiac patients had significantly higher carotid intima media thickness and carotid pulse wave velocity values, there was no difference in the augmentation index values. There was no significant difference in carotid artery intimal medial thickness, augmentation index and carotid pulse wave velocity values between the diet-compliant and non-compliant groups. Conclusion: Although hypertension was not detected, arterial stiffness and carotid intima media thickness measurements were higher in the celiac disease patients compared to the healthy controls. This showed that these parameters can be used in early vascular damage assessment. These measurements, which are non-invasive and repeatable, can be a guide for the monitoring of the development of preclinical atherosclerosis in the follow-up of the pediatric patients diagnosed with celiac disease.en_US
dc.identifier.doi10.4274/jpr.galenos.2023.67503
dc.identifier.endpage172en_US
dc.identifier.issn2147-9445
dc.identifier.issue3en_US
dc.identifier.startpage167en_US
dc.identifier.urihttps://doi.org/10.4274/jpr.galenos.2023.67503
dc.identifier.urihttps://hdl.handle.net/11454/104236
dc.identifier.volume10en_US
dc.identifier.wosWOS:001144653500001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofJournal of Pediatric Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240831_Uen_US
dc.subjectAixen_US
dc.subjectCeliac Diseaseen_US
dc.subjectChildrenen_US
dc.subjectCimten_US
dc.subjectPwven_US
dc.titleEvaluation of Vascular Involvement in Children with Celiac Diseaseen_US
dc.typeArticleen_US

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