The Prophylaxis of Febrile Convulsions in Childhood: Secular Trends in the Last Decade (2007-2008 versus 2017-2018)

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dc.authoridKanmaz, Seda/0000-0002-8738-1242
dc.contributor.authorKanmaz, Seda
dc.contributor.authorAtas, Yavuz
dc.contributor.authorToprak, Dilara Ece
dc.contributor.authorHoscoskun, Elif
dc.contributor.authorOlculu, Cemile Busra
dc.contributor.authorInce, Tugce
dc.contributor.authorYilmaz, Ozlem
dc.date.accessioned2024-08-25T18:48:30Z
dc.date.available2024-08-25T18:48:30Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: To analyze trends in the prophylaxis of febrile convulsions (FC) in childhood by comparing two cohorts from the previous two decades (2007-2008 versus 2017-2018).Materials and Methods: The cohort consisted of 272 children with FC who were followed up during the 2007-2008 (n=105) and 2017-2018 (n=167) periods in Ege University Faculty of Medicine Children's Hospital. The following clinical parameters were analyzed: demographic data, FC types, prophylaxis types, selected anti-seizure medications (ASM), recurrence risk factors, and electroencephalography (EEG) characteristics.Results: We defined two secular trends for the prophylaxis of FC in children in the last decade: (1) a reduced rate of FC prophylaxis (22.1%) in the period of 2017-2018 compared with a rate of 63.8% in 2007-2008, p<0.01, (2) no impact of recurrence risk factors for the initiation of prophylaxis for complex FC in the last decade (p=0.028). The mean number of previous seizures at the initiation of the ASM prophylaxis increased from 2.8 +/- 1.13 to 3.4 +/- 2.00 for simple FC and from 1.9 +/- 0.24 to 3.1 +/- 0.31 for complex FC (p<0.01) in the period of 2017-2018.Conclusion: Prophylaxis rates were determined to be lower in the last decade in children with FC. There was no impact of recurrence risk factors for the initiation of prophylaxis in children with simple or complex FC.en_US
dc.identifier.doi10.4274/jpr.galenos.2022.87847
dc.identifier.endpage25en_US
dc.identifier.issn2147-9445
dc.identifier.issue1en_US
dc.identifier.startpage19en_US
dc.identifier.urihttps://doi.org/10.4274/jpr.galenos.2022.87847
dc.identifier.urihttps://hdl.handle.net/11454/102297
dc.identifier.volume10en_US
dc.identifier.wosWOS:000942583000005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofJournal of Pediatric Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240825_Gen_US
dc.subjectFebrile convulsionen_US
dc.subjectASM prophylaxisen_US
dc.subjectfebrile convulsion recurrence risk factorsen_US
dc.subjectRisk-Factorsen_US
dc.subjectSeizuresen_US
dc.subjectRecurrenceen_US
dc.subjectManagementen_US
dc.subjectDiazepamen_US
dc.titleThe Prophylaxis of Febrile Convulsions in Childhood: Secular Trends in the Last Decade (2007-2008 versus 2017-2018)en_US
dc.typeArticleen_US

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