Early and Late Side Effects Associated with Photo(chemo)therapy

dc.contributor.authorOzturk, Gunseli
dc.date.accessioned2019-10-27T21:29:35Z
dc.date.available2019-10-27T21:29:35Z
dc.date.issued2010
dc.departmentEge Üniversitesien_US
dc.description.abstractPhototherapy (PUVA ye UVB) is a widely used and effective treatment method for a variety of dermatological diseases. Adverse effects associated with phototherapy can be classified as acute and chronic side effects. Acute side effects are mostly related with UV doses and drug intolerance, and include itching, nausea, erythema, edema and phototoxic reactions that sometimes blister formation is seen. Acute side effects are usually moderate and transient. Chronic side effects of phototherapy are early aging of skin, pigmentary changes and increased risk of skin carcinogenesis. The major concern is development of skin cancer. This risk is especially related to long-term exposure and high cumulative doses of PUVA, increase in time and is persistent. Therefore, risk/advantage ratio of phototherapy should be carefully evaluated in each patient, and treatment protocols with minimal UV exposure should be chosen according to the phototherapy guides. Follow-up of the patients for long terms is important in prevention or in reduction of this risk by detecting and treating any premalignant or malignant lesion early. In this article, acute and chronic side effects of phototherapy are reviewed with recent literature findings.en_US
dc.identifier.doi10.4274/turkderm.44.s86
dc.identifier.endpage90en_US
dc.identifier.issn1019-214X
dc.identifier.issn1308-6294
dc.identifier.issn1019-214Xen_US
dc.identifier.issn1308-6294en_US
dc.identifier.startpage86en_US
dc.identifier.urihttps://doi.org/10.4274/turkderm.44.s86
dc.identifier.urihttps://hdl.handle.net/11454/45294
dc.identifier.volume44en_US
dc.identifier.wosWOS:000209333700005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherDeri Zuhrevi Hastaliklar Dernegien_US
dc.relation.ispartofTurkderm-Turkish Archives of Dermatology and Venerologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPhotochemotherapyen_US
dc.subjectUVB phototherapyen_US
dc.subjectside effectsen_US
dc.titleEarly and Late Side Effects Associated with Photo(chemo)therapyen_US
dc.typeArticleen_US

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