Measles revaccination response in 4-7-year-old children
Küçük Resim Yok
Tarih
1995
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In Turkey, two measles outbreaks occurred in 1989 and 1993. The majority of cases has been previously vaccinated children. We evaluated the necessity of measles revaccination in 4-7-year-old children by establishing the increase in anti-measles IgG level following revaccination, and by determining the percentage of measles-susceptible subjects in previously vaccinated children. Seventy-five children were revaccinated and sera were collected just prior to revaccination and after two weeks. Anti-measles IgG titers were determined by enzyme immunoassay. Four-fold and greater increases in anti-measles IgG titers were obtained in 17.3% of children, and they were defined as immunologically susceptible to measles. Pre-revaccination measles specific IgG titers less than 3224 ng/ml were a significant risk factor for measles susceptibility. None of the revaccinated children had notable complications. These data support the necessity and safety of measles revaccination.
Açıklama
Anahtar Kelimeler
immunization, measles antibodies, measles vaccine
Kaynak
Turkish Journal of Medical Sciences
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
25
Sayı
1
