Evaluation of a Neuropsychiatric Disorder: From PANDAS to PANS and CANS

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dc.contributor.authorBaytunca, Muharrem Burak
dc.contributor.authorDonuk, Tugba
dc.contributor.authorErermis, Serpil
dc.date.accessioned2019-10-27T23:09:34Z
dc.date.available2019-10-27T23:09:34Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractPANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections) syndrome is a disorder seen before adolescence that possesses an abrupt onset of obsessive compulsive disorder symptoms and/or tics. Swedo and colleagues defined this disorder in 1998 as a syndrome related to Group A streptoccoccus (GAS) infection with neurological issues, such as motor hyperactivation and choreiform movements. The progress of the disorder may be described as wax-and-waning, apart from abrupt onset, and this relapse and remission course is associated with exacerbating infections, according to the creators of PANDAS syndrome Ruling out of Rheumatoid Fever and Sydenham's Chorea was a necessity for making a proper diagnosis. Since the recognition of this syndrome, clinicians encountered many children who could not fulfill all 5 criteria, which must be met for PANDAS diagnosis. In addition, due to literature showing failure and lack of strong evidence of a major role of GAS, the newly-defined categories PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and CANS (Childhood Acute Neuropsychiatric Syndrome) were created to encompass those of "almost met" non-PANDAS cases. PANS and CANS include concurrent significant psychiatric symptoms with abrupt onset of OCD symptoms and/or tics but do not require identification of any infection agent, immune dysfunction, or enviromental precipitants. In this paper, we aimed to discuss PANS/CANS, alterations of PANDAS, and diagnoses in which "almost met" PANDAS patients should be classified on the basis of a case who developed an abrupt onset of anxiety, obsessions, and vocal tics.en_US
dc.identifier.doi10.5080/u12265
dc.identifier.endpage146en_US
dc.identifier.issn1300-2163
dc.identifier.issn1300-2163en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage143en_US
dc.identifier.urihttps://doi.org/10.5080/u12265
dc.identifier.urihttps://hdl.handle.net/11454/52688
dc.identifier.volume27en_US
dc.identifier.wosWOS:000379451400009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherTurkiye Sinir Ve Ruh Sagligi Dernegien_US
dc.relation.ispartofTurk Psikiyatri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infectionsen_US
dc.subjectObsessive-Compulsive Disorderen_US
dc.subjectstreptococcal infectionsen_US
dc.subjecttic disordersen_US
dc.titleEvaluation of a Neuropsychiatric Disorder: From PANDAS to PANS and CANSen_US
dc.typeArticleen_US

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