Dipeptidyl peptidase IV production by solid state fermentation using alternative fungal sources

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dc.contributor.authorOngen, Gaye
dc.contributor.authorSargin, Sayit
dc.contributor.authorUstun, Ozlem
dc.contributor.authorKutlu, Ceren
dc.contributor.authorYucel, Mesut
dc.date.accessioned2019-10-27T21:33:50Z
dc.date.available2019-10-27T21:33:50Z
dc.date.issued2012
dc.departmentEge Üniversitesien_US
dc.description.abstractThe present work was carried out for the production of dipeptidyl peptidase IV (DPP IV; EC 3.4.14.5) using Aspergillus, Penicillium, and Rhizopus strains under solid state fermentation conditions. Response surface methodology was applied for the optimization of the selected operational variables (corn flour, initial moisture content, and cultivation time) for DPP IV activity as the response. The optimal parameters of DPP IV activity for the independent variables, namely the amount of corn flour (% w/w), initial moisture content (% w/w), and cultivation time (days), were evaluated to be 2.44%, 60.85%, and 4.69 days, respectively, using Aspergillus awamori T116. The response for these results was also shown to be in very close agreement with the experimental data.en_US
dc.description.sponsorshipTUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [105T195]en_US
dc.description.sponsorshipWe thank Sevket Karacanci (PhD) for using the Design Expert software (version 7.1.6, Stat-Ease, Inc.). This study was supported by TUBITAK, project number 105T195.en_US
dc.identifier.doi10.3906/biy-1201-26
dc.identifier.endpage671en_US
dc.identifier.issn1300-0152
dc.identifier.issn1300-0152en_US
dc.identifier.issue6en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage665en_US
dc.identifier.urihttps://doi.org/10.3906/biy-1201-26
dc.identifier.urihttps://hdl.handle.net/11454/45428
dc.identifier.volume36en_US
dc.identifier.wosWOS:000312424500007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDipeptidyl peptidase IVen_US
dc.subjectAspergillusen_US
dc.subjectPenicilliumen_US
dc.subjectRhizopusen_US
dc.subjectsolid state fermentationen_US
dc.titleDipeptidyl peptidase IV production by solid state fermentation using alternative fungal sourcesen_US
dc.typeArticleen_US

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