Location of the contrast extravasation is important in predicting outcome of anterior circulation stroke patients

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dc.contributor.authorOzdemir, Huseyin Nezih
dc.contributor.authorKaraman, Bedriye
dc.contributor.authorGuler, Ayse
dc.contributor.authorDere, Birgul
dc.contributor.authorCinar, Celal
dc.contributor.authorKumral, Dursun Emre
dc.contributor.authorSirin, Hadiye
dc.date.accessioned2024-08-31T07:50:28Z
dc.date.available2024-08-31T07:50:28Z
dc.date.issued2024
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectives: Contrast extravasations (CE) are frequently seen on postprocedural computed tomography after endovascular therapy (EVT). This study aimed to investigate the relationship between patients' outcomes and CE after EVT. Methods: Stroke patients who had received EVT between 2019 and 2021 were reviewed retrospectively. The CEs were mapped using MRIcroGL software. The rate of in-hospital mortality and modified Rankin Scale at 90 days were taken as outcome measures. Stepwise logistic regression analyses were performed. Three models were created with and without pure CE to predict the patients' outcomes. Results: There were 126 patients included in the study. According to the univariable analysis, CE (OR = 0.70, 95% CI = 0.18-2.68, P = 0.26) and CE-ASPECTS (OR = 1.21, 95% CI=0.60-2.44, P = 0.57) were not related with in-hospital mortality after EVT. The lesion mapping showed that the most common CE locations among the patients with a poor prognosis was the M6 area. The multivariable logistic regression analysis showed that CE in the M6 area (OR = 6.87, 95% CI = 1.27-144.92, P = 0.006) increased the risk of a 3-month poor outcome. The study showed that adding CE to the well-known risk factors for poor prognosis improves the predictive power of the models (Delta AUC of 0.07, P = 0.02). Conclusion: CE has a prognostic value after EVT in anterior stroke patients. The prognostic value is the highest when present in the M6 area.en_US
dc.description.sponsorshipEthics: The local ethics committee of the Ege University Medical School approved the study. Ethics committee number: 99166796-050.06.04- 1017839/Date: 06.12.2022. Informed consent was obtained from all participants of the study. Financial support: None Conflict of interests: Noneen_US
dc.identifier.doi10.54029/2024wcy
dc.identifier.endpage320en_US
dc.identifier.issn1823-6138
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85198627023en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage311en_US
dc.identifier.urihttps://doi.org/10.54029/2024wcy
dc.identifier.urihttps://hdl.handle.net/11454/105240
dc.identifier.volume29en_US
dc.identifier.wosWOS:001262534800004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAsean Neurological Assocen_US
dc.relation.ispartofNeurology Asiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240831_Uen_US
dc.subjectStrokeen_US
dc.subjectEndovascular Therapyen_US
dc.subjectContrast Extravasationen_US
dc.subjectPrognosisen_US
dc.titleLocation of the contrast extravasation is important in predicting outcome of anterior circulation stroke patientsen_US
dc.typeArticleen_US

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